News tagged with mitotic checkpoint
Death, division or cancer? Newly discovered checkpoint process holds the line in cell division
Jul 01, 2008 |
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Each day, a staggering number of cells perform a feat that still amazes researchers with its complexity: they divide to produce perfect replicas of each other. The process is called mitosis, and an inability to control it ...
Search results for mitotic checkpoint
A breakthrough in gastric carcinogenesis
Jun 11, 2009 |
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Checkpoint with forkhead and ring finger (CHFR) is a mitotic stress checkpoint gene whose promoter is frequently methylated in various kinds of cancer. In gastric cancer, CHFR promoter hypermethylation has been reported to ...
Researchers illuminate mechanisms that regulate DNA damage control and replication
Biology /
Jan 05, 2009 |
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Scientists at Burnham Institute for Medical Research (Burnham) have demonstrated important new roles for the protein kinase complex Cdc7/Dbf4 or Cdc7/Drf1 (Ddk) in monitoring damage control during DNA replication and reinitiating ...
Stem-cell sentry sounds the alarm to maintain balance between cancer and aging
Oct 15, 2008 |
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(PhysOrg.com) -- Like a sentry guarding the castle walls, a molecular messenger inside adult stem cells sounds the alarm when it senses hazards that could allow the invasion of an insidious enemy: Cancer. The alarm bell halts ...
New research shows key player in mitosis not required for chromosome alignment
Jul 06, 2009 |
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(PhysOrg.com) -- K-fibers, structures long thought to play a key role in the alignment of chromosomes prior to cell division, are not required after all, say Indiana University and New York State Department ...
A new cellular pathway linked to cancer is identified
Jul 24, 2008 |
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In the life of a cell, the response to DNA damage determines whether the cell is fated to pause and repair itself, commit suicide, or grow uncontrollably, a route leading to cancer. In a new study, published in the July 25th ...
How chemo kills tumours: research to reduce side effects
Aug 01, 2008 |
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(PhysOrg.com) -- University of Manchester researchers are investigating exactly how chemotherapy drugs kill cancerous tumours in a bid to reduce side effects and test the effectiveness of safer new agents.
Lack of CHFR gene expression sets stage for breast cancer
Jun 19, 2008 |
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[B]U-M study lays groundwork for better ways to choose effective treatments, provides insights on other cancers[/B] A University of Michigan study reveals in detail how breast cells produce new cells tha ...
Chemotherapy resistance: Checkpoint protein provides armor against cancer drugs
Aug 27, 2009 |
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Cell cycle checkpoints act like molecular tripwires for damaged cells, forcing them to pause and take stock. Leave the tripwire in place for too long, though, and cancer cells will press on regardless, making ...
Researchers unveil vital key to cancer
Aug 06, 2008 |
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University of Manchester scientists have uncovered the 3-D structure of Mps1 -- a protein that regulates the number of chromosomes during cell division and thus has an essential role in the prevention of cancer -- which will ...
Researchers shed light on how tumor cells form
Jun 21, 2006 |
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MIT cancer researchers have discovered a process that may explain how some tumor cells form, a discovery that could one day lead to new therapies that prevent defective cells from growing and spreading.
List of search results for mitotic checkpoint
