News tagged with modifications

ACP recommends metformin to treat type 2 diabetes based on CE analysis of oral medications

The American College of Physicians (ACP) recommends that clinicians add metformin as the initial drug treatment for most patients with type 2 diabetes when lifestyle modifications such as diet, exercise, and weight loss have ...

Medicine & Health / Diseases

created Feb 06, 2012 | popularity not rated yet | comments 0

Ancient DNA holds clues to climate change adaptation

(PhysOrg.com) -- Thirty-thousand-year-old bison bones discovered in permafrost at a Canadian goldmine are helping scientists unravel the mystery about how animals adapt to rapid environmental change.

Biology / Plants & Animals

created Jan 31, 2012 | popularity not rated yet | comments 0 | with audio podcast

Understanding the structure of the TAL effector may be key for targeted gene correction

Researchers at Fred Hutchinson Cancer Research Center have solved the three-dimensional structure of a newly discovered type of gene-targeting protein that has shown to be useful as a DNA-targeting molecule for gene correction, ...

Medicine & Health / Genetics

created Jan 05, 2012 | popularity not rated yet | comments 1 | with audio podcast

Scientists engineer mosquito immune system to fight malaria

Researchers at the Johns Hopkins Malaria Research Institute have demonstrated that the Anopheles mosquito's innate immune system could be genetically engineered to block the transmission of malaria-causing parasites to humans. ...

Medicine & Health / Diseases

created Dec 22, 2011 | popularity not rated yet | comments 0

Scientists elevate little-studied cellular mechanism to potential drug target

For years, science has generally considered the phosphorylation of proteins -- the insertion of a phosphorous group into a protein that turns it on or off -- as perhaps the factor regulating a range of cellular processes ...

Chemistry / Biochemistry

created Dec 11, 2011 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Unique genetic marker may improve detection of recurrent ovarian cancer

Ovarian cancer is a major health concern for women and the identification of sensitive biomarkers for early detection and/or monitoring of disease recurrence is of high clinical relevance.

Medicine & Health / Cancer

created Dec 07, 2011 | popularity not rated yet | comments 0

Lessons learned from yeast about human leukemia

The trifecta of biological proof is to take a discovery made in a simple model organism like baker's yeast and track down its analogs or homologs in "higher" creatures right up the complexity scale to people, ...

Biology / Cell & Microbiology

created Dec 05, 2011 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Study identifies mechanisms cells use to remove bits of RNA from DNA strands

When RNA component units called ribonucleotides become embedded in genomic DNA, which contains the complete genetic data for an organism, they can cause problems for cells. It is known that ribonucleotides ...

Medicine & Health / Cancer

created Dec 04, 2011 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Flies can pass the effects of stress to their young in the form of chromosomal modifications

Most people don’t realize the extent of the biochemical and physiological changes that stress causes; indeed, new research suggests that offspring might even be vulnerable to changes in gene expression ...

Biology / Biotechnology

created Nov 11, 2011 | popularity 5 / 5 (3) | comments 4

Patterns of new DNA letter in brain suggest distinct function

In 2009, the DNA alphabet expanded. Scientists discovered that an extra letter or "sixth nucleotide" was surprisingly abundant in DNA from stem cells and brain cells.

Medicine & Health / Neuroscience

created Oct 30, 2011 | popularity 5 / 5 (8) | comments 0 | with audio podcast

UK scientists grow super broccoli

Popeye might want to consider switching to broccoli. British scientists recently unveiled a new breed of the vegetable that experts say packs a big nutritional punch.

Biology / Plants & Animals

created Oct 26, 2011 | popularity 5 / 5 (1) | comments 3

Propensity for longer life span inherited non-genetically over generations, study says

We know that our environment -- what we eat, the toxic compounds we are exposed to -- can positively or negatively impact our life span. But could it also affect the longevity of our descendants, who may live under very different ...

Biology / Biotechnology

created Oct 19, 2011 | popularity 5 / 5 (2) | comments 1 | with audio podcast

Scientists discover 'fickle' DNA changes in brain

Johns Hopkins scientists investigating chemical modifications across the genomes of adult mice have discovered that DNA modifications in non-dividing brain cells, thought to be inherently stable, instead underwent large-scale ...

Medicine & Health / Neuroscience

created Sep 30, 2011 | popularity 4.4 / 5 (5) | comments 1 | with audio podcast

Epigenetic changes don't last

Jean-Baptiste Lamarck would have been delighted: geneticists no longer dismiss out of hand his belief that acquired traits can be passed on to offspring. When Darwin published his book on evolution, Lamarck's ...

Biology / Evolution

created Sep 20, 2011 | popularity 5 / 5 (4) | comments 2 | with audio podcast

Treatment of CV risk factors appears to improve sexual function in men with erectile dysfunction

Lifestyle modifications and pharmaceutical treatment of risk factors for cardiovascular disease are associated with improvement in sexual function among men with erectile dysfunction (ED), according to a meta-analysis posted ...

Medicine & Health / Health

created Sep 12, 2011 | popularity 5 / 5 (1) | comments 0