News tagged with monoclonal antibodies

Rituximab possible treatment option for patients with primary biliary cirrhosis

An open-label study of rituximab, a monoclonal antibody for human CD20, was shown to be safe in patients with primary biliary cirrhosis (PBC) who had an incomplete response to the standard ursodeoxycholic acid (UDCA) therapy, ...

Medicine & Health / Diseases

created Feb 02, 2012 | popularity not rated yet | comments 0

Study identifies a cause of resistance to colon cancer treatment

Doctors and researchers of Hospital del Mar and its research institute, the IMIM, have lead a study describing a new pharmacological resistance to cancer. This new mechanism is a mutation in an oncogene called EGFR (epidermal ...

Medicine & Health / Cancer

created Jan 22, 2012 | popularity 5 / 5 (1) | comments 0

A new way to stimulate the immune system and fight infection

A study carried out by Eric Vivier and Sophie Ugolini at the Marseille-Luminy Centre for Immunology has just reveal a gene in mice which, when mutated, can stimulate the immune system to help fight against tumors and viral ...

Medicine & Health / Research

created Jan 20, 2012 | popularity 5 / 5 (3) | comments 0

RTOG initiates a phase I trial testing the therapy ganitumab for locally advanced pancreatic cancer

Over 17,000 patients will have been diagnosed with locally-advanced pancreatic cancer in the United States in 2011. Surgery is not a treatment option for these patients whose tumor has grown beyond the pancreas to surrounding ...

Medicine & Health / Cancer

created Dec 14, 2011 | popularity 5 / 5 (2) | comments 0

More intensive chemotherapy dramatically improves recurrence, survival in younger patients with aggressive lymphoma

Younger patients with diffuse large B-cell lymphoma given a more intensive regimen of chemotherapy combined with rituximab survive significantly longer, and are approximately twice as likely to remain in remission 3 years ...

Medicine & Health / Cancer

created Nov 24, 2011 | popularity not rated yet | comments 0

New treatment for Multiple Sclerosis: Cambridge University translates research at the bench into a drug at the bedside

The culmination of three decades of research in Cambridge has resulted in the exciting prospect of a new transformational treatment for multiple sclerosis.

Medicine & Health / Research

created Nov 15, 2011 | popularity not rated yet | comments 0

Injection lowers cholesterol in preliminary human trial

Patients unable to control their cholesterol levels with medications may someday be able to lower their "bad" cholesterol with a shot, according to research presented at the American Heart Association's Scientific Sessions ...

Medicine & Health / Cardiology

created Nov 14, 2011 | popularity 2.3 / 5 (3) | comments 2

Combination therapy shows potent tumor growth inhibition in preclinical studies

Combining the investigational agents REGN910 and aflibercept yielded statistically significant improvements in antitumor effects in animal models compared with either agent alone, according to results presented at the AACR-NCI-EORTC ...

Medicine & Health / Cancer

created Nov 13, 2011 | popularity not rated yet | comments 0

New target identified to stop the spread of breast cancer

A new potential target to slow breast cancer tumor progression and metastasis has been identified by a team of researchers led by Dr. Richard Kremer from the Research Institute of the McGill University Health Centre (RI-MUHC). ...

Medicine & Health / Cancer

created Nov 10, 2011 | popularity 5 / 5 (1) | comments 0

Experimental drug suppresses rebound of hepatitis C virus in liver transplant patients

A human monoclonal antibody developed by MassBiologics of the University of Massachusetts Medical School (UMMS) given to patients with chronic hepatitis C virus (HCV) infection undergoing liver transplantation significantly ...

Medicine & Health / Diseases

created Nov 07, 2011 | popularity not rated yet | comments 0

New findings may help explain high blood pressure in pregnancy

Virginia Commonwealth University School of Medicine researchers have discovered that the infiltration of white blood cells into an expectant mother's blood vessels may explain high blood pressure in pregnancy.

Medicine & Health / Research

created Oct 31, 2011 | popularity not rated yet | comments 0 | with audio podcast

Major advance in the treatment of Hendra virus reported

A collaborative research team from Boston University School of Medicine (BUSM), the Uniformed Services University of the Health Sciences (USU), the University of Texas Medical Branch (UTMB) and Galveston National ...

Medicine & Health / Research

created Oct 19, 2011 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Biological agents for rheumatoid arthritis associated with increased skin cancer risk

Biological agents used to treat rheumatoid arthritis seem to be associated with an increased risk of skin cancer, indicates a systematic review of published research in the Annals of the Rheumatic Diseases.

Medicine & Health / Cancer

created Sep 08, 2011 | popularity 3 / 5 (2) | comments 0

Humabs discovers the first antibody to neutralize both group 1 and group 2 influenza A viruses

A paper published today in the scientific research journal Science, describes a novel, proprietary monoclonal antibody (FI6) discovered in a collaboration between Humabs BioMed SA, the Institute for Research in Biomedicine ("IRB" ...

Medicine & Health / Research

created Jul 28, 2011 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Clinical tests for medicines made from genetically modified plants

UK regulators have approved Europe's first clinical trial of a monoclonal antibody produced from genetically modified plants. This landmark decision sets the stage for the testing, in humans, of an anti-HIV product made from ...

Medicine & Health / Other

created Jul 21, 2011 | popularity not rated yet | comments 0

Monoclonal antibodies

Monoclonal antibodies (mAb or moAb) are monospecific antibodies that are identical because they are produced by one type of immune cell that are all clones of a single parent cell. Given almost any substance, it is possible to create monoclonal antibodies that specifically bind to that substance; they can then serve to detect or purify that substance. This has become an important tool in biochemistry, molecular biology and medicine. When used as medications, the generic drug name ends in -mab (see "Nomenclature of monoclonal antibodies").

For more information about Monoclonal antibodies, read the full article at Wikipedia.
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