News tagged with mouse cells
Cure of ADPKD by selection for spontaneous genetic repair events in Pkd1-mutated iPS cells
A research group including Kyoto University researchers demonstrates that mouse iPS cells, in which genetic correction occurs spontaneously through mitotic recombination, is selectable from the population of genetically mutated ...
13 hours ago |
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Scientists use an old theory to discover new targets in the fight against breast cancer
Reviving a theory first proposed in the late 1800s that the development of organs in the normal embryo and the development of cancers are related, scientists at the Salk Institute for Biological Studies have ...
Feb 07, 2012 |
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Drugs targeting chromosomal instability may fight a particular breast cancer subtype
Another layer in breast cancer genetics has been peeled back. A team of researchers at Jefferson's Kimmel Cancer Center (KCC) led by Richard G. Pestell, M.D., PhD., FACP, Director of the KCC and Chair of the Department of ...
Feb 06, 2012 |
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Why two new studies represent important breakthrough in Alzheimer's disease research
Two different research groups have independently made the same important discoveries on how Alzheimer's disease spreads in the brain. The groups' findings have the potential to give us a much more sophisticated understanding ...
Medicine & Health / Neuroscience
Feb 03, 2012 |
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Study shows Alzheimer's disease may spread by 'jumping' from one brain region to another
For decades, researchers have debated whether Alzheimer's disease starts independently in vulnerable brain regions at different times, or if it begins in one region and then spreads to neuroanatomically connected areas. A ...
Medicine & Health / Neuroscience
Feb 01, 2012 |
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SUMO-snipping protein plays crucial role in T and B cell development
When SUMO grips STAT5, a protein that activates genes, it blocks the healthy embryonic development of immune B cells and T cells unless its nemesis breaks the hold, a research team led by scientists at The University of Texas ...
Jan 27, 2012 |
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Grape seed extract kills head and neck cancer cells, leaves healthy cells unharmed
Nearly 12,000 people will die of head and neck cancer in the United States this year and worldwide cases will exceed half a million.
Jan 27, 2012 |
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Investigators achieve important step toward treating Huntington's disease
A team of researchers at the UC Davis Institute for Regenerative Cures has developed a technique for using stem cells to deliver therapy that specifically targets the genetic abnormality found in Huntington's disease, a hereditary ...
Medicine & Health / Neuroscience
Jan 19, 2012 |
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Study reveals origins of esophageal cancer
(Medical Xpress) -- Researchers at Columbia University Medical Center (CUMC) have identified the critical early cellular and molecular events that give rise to a type of esophageal cancer called esophageal ...
Jan 17, 2012 |
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Some breast cancer spread may be triggered by a protein, study shows
Cancers rarely are deadly unless they evolve the ability to grow beyond the tissues in which they first arise. Normally, cells -- even early-stage tumor cells -- are tethered to scaffolding that helps to restrain ...
Jan 17, 2012 |
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Autism may be linked to abnormal immune system characteristics and novel protein fragment
Immune system abnormalities that mimic those seen with autism spectrum disorders have been linked to the amyloid precursor protein (APP), reports a research team from the University of South Florida's Department of Psychiatry ...
Jan 03, 2012 |
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A firmer understanding of muscle fibrosis
Researchers describe how increased production of a microRNA promotes progressive muscle deterioration in a mouse model of Duchenne muscular dystrophy (DMD), according to a study published online on January ...
Jan 02, 2012 |
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Double trouble: Concomitant immune challenges result in CNS disease
A research team led by Glenn Rall at the Fox Chase Cancer Center in Philadelphia, PA developed a novel mouse model to show that a fatal central nervous system (CNS) disease can be caused by a pathogen that does not replicate ...
Dec 22, 2011 |
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Regulatory enzyme overexpression may protect against neurodegeneration in Huntington's disease
Treatment that increases brain levels of an important regulatory enzyme may slow the loss of brain cells that characterizes Huntington's disease (HD) and other neurodegenerative disorders. In a report receiving advance online ...
Medicine & Health / Neuroscience
Dec 18, 2011 |
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A gene that protects against colorectal cancers
The research team in France has developed an animal model carrying a mutation of the DCC gene. Mice carrying the mutation develop tumours, because this gene can no longer induce the death of the cancer cells. This discovery ...
Dec 14, 2011 |
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