News tagged with mouse model
Related topics: stem cells , proceedings of the national academy of sciences , mice , cancer , bone marrow
Cure of ADPKD by selection for spontaneous genetic repair events in Pkd1-mutated iPS cells
A research group including Kyoto University researchers demonstrates that mouse iPS cells, in which genetic correction occurs spontaneously through mitotic recombination, is selectable from the population of genetically mutated ...
Feb 10, 2012 |
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Why two new studies represent important breakthrough in Alzheimer's disease research
Two different research groups have independently made the same important discoveries on how Alzheimer's disease spreads in the brain. The groups' findings have the potential to give us a much more sophisticated understanding ...
Medicine & Health / Neuroscience
Feb 03, 2012 |
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Grape seed extract kills head and neck cancer cells, leaves healthy cells unharmed
Nearly 12,000 people will die of head and neck cancer in the United States this year and worldwide cases will exceed half a million.
Jan 27, 2012 |
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Multiple births lead to weight gain and other problems for mouse moms and male offspring
Women have long bemoaned the fact that as they have more children, their weight gain from pregnancy becomes more difficult to lose. A new study using a mouse model that mimics the human effects of multiparity (giving birth ...
Jan 26, 2012 |
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Mutation drives viral sensors to initiate autoimmune disease
A new study uses a mouse model of a human autoimmune disease to reveal how abnormal regulation of the intracellular sensors that detect invading viruses can lead to autoimmune pathology. The research, published online on ...
Jan 26, 2012 |
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Escape from the mouse trap? New experimental models developing
(Medical Xpress) -- Mark Davis, PhD, director of Stanfords Institute for Immunity, Transplantation and Infection, has used mice to brilliant effect. They have helped him and a legion of fellow immunologists unravel many ...
Jan 23, 2012 |
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Gold nanorods could improve radiation therapy of head and neck cancer
Radiation therapy is an important part of head and neck cancer therapy, but most head and neck tumors have a built-in mechanism that makes them resistant to radiation. As a result, oncologists have to deliver huge doses of ...
Nanotechnology / Bio & Medicine
Jan 20, 2012 |
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Single dose of antibiotic leaves mice highly vulnerable to intestinal infection
Yet another study adds to the growing evidence that antibiotics can disrupt the balance of the intestinal flora, with negative effects on health. A team of researchers from the Memorial Sloan Kettering Cancer Center, New ...
Jan 20, 2012 |
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Investigators achieve important step toward treating Huntington's disease
A team of researchers at the UC Davis Institute for Regenerative Cures has developed a technique for using stem cells to deliver therapy that specifically targets the genetic abnormality found in Huntington's disease, a hereditary ...
Medicine & Health / Neuroscience
Jan 19, 2012 |
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Some breast cancer spread may be triggered by a protein, study shows
Cancers rarely are deadly unless they evolve the ability to grow beyond the tissues in which they first arise. Normally, cells -- even early-stage tumor cells -- are tethered to scaffolding that helps to restrain ...
Jan 17, 2012 |
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New automated imaging to greatly speed whole-brain mapping efforts
A new technology developed by neuroscientists at Cold Spring Harbor Laboratory (CSHL) transforms the way highly detailed anatomical images can be made of whole brains. Until now, means of obtaining such images ...
Jan 15, 2012 |
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Study finds two genes affect anxiety, behavior in mice with too much MeCP2
The anxiety and behavioral issues associated with excess MeCP2 protein result from overexpression of two genes (Crh [corticotropin-releasing hormone] and Oprm 1 [mu-opioid receptor MOR 1]), which may point the way to treating ...
Jan 08, 2012 |
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Diabetic mice provide a surprising breakthrough for multiple sclerosis research
(Medical Xpress) -- In humans, active periods of the debilitating disease Multiple Sclerosis (MS) can last for mere minutes or extend to weeks at a time. They're caused by lesions in the brain that develop, ...
Medicine & Health / Neuroscience
Jan 05, 2012 |
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Autism may be linked to abnormal immune system characteristics and novel protein fragment
Immune system abnormalities that mimic those seen with autism spectrum disorders have been linked to the amyloid precursor protein (APP), reports a research team from the University of South Florida's Department of Psychiatry ...
Jan 03, 2012 |
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A firmer understanding of muscle fibrosis
Researchers describe how increased production of a microRNA promotes progressive muscle deterioration in a mouse model of Duchenne muscular dystrophy (DMD), according to a study published online on January ...
Jan 02, 2012 |
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