News tagged with mouse model
Cellular crosstalk linked to lung disease
Aug 18, 2009 |
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Crosstalk between cells lining the lung (epithelial cells) and airway smooth muscle cells is important in lung development. However, it has also been shown to contribute to several lung diseases, including asthma and pulmonary ...
Some mice stem cells divide in unexpected ways
Aug 14, 2009 |
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(PhysOrg.com) -- Using new genetic tools, Cornell researchers have found that some stem cells in mice behave dramatically different than in fruit flies, where most of the pioneering stem cell work has been ...
Traffic jam in brain causes schizophrenia symptoms
Medicine & Health / Neuroscience
Aug 10, 2009 |
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Schizophrenia waits silently until a seemingly normal child becomes a teenager or young adult. Then it swoops down and derails a young life.
Unlikely genetic suspect implicated in common brain defect
Aug 09, 2009 |
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A genetic search that wound its way from patients to mouse models and back to patients has uncovered an unlikely gene critically involved in a common birth defect which causes mental retardation, motor delays ...
Finding key to cancer drug Gleevec's limitations
Aug 05, 2009 |
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University of Michigan researchers have developed an animal model that provides strong evidence why imatinib, marketed as Gleevec, helps patients with chronic myeloid leukemia survive longer, but does not ...
Silenced genes as a warning sign of blood cancer
Aug 04, 2009 |
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In many types of cancer, parts of the genetic material of tumor cells are switched off by chemical labels called methyl groups. This kind of methyl labeling ranges among the epigenetic changes that do not change the sequence ...
Researchers effectively treat tumors with use of nanotubes
Nanotechnology / Bio & Medicine
Aug 03, 2009 |
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By injecting man-made, microscopic tubes into tumors and heating them with a quick, 30-second zap of a laser, scientists have discovered a way to effectively kill kidney tumors in nearly 80 percent of mice. Researchers say ...
New way to fight drug-resistant fungal infections discovered
Jul 31, 2009 |
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(PhysOrg.com) -- The secret to fighting often lethal drug resistant fungal infections is to knock out the bug's molecular chaperone, according to U of T researchers.
Nanoparticle-delivered 'suicide' genes slowed ovarian tumor growth (w/ Video)
Jul 30, 2009 |
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Nanoparticle delivery of diphtheria toxin-encoding DNA selectively expressed in ovarian cancer cells reduced the burden of ovarian tumors in mice, and researchers expect this therapy could be tested in humans within 18 to ...
Assisted reproductive techniques alter the expression of genes that are important for metabolism
Jul 27, 2009 |
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Research to be presented at the Annual Meeting of the Society for the Study of Ingestive Behavior (SSIB), the foremost society for research into all aspects of eating and drinking behavior, finds that assisted reproductive ...
Preimplantation genetic diagnosis may pose neurological risks
Jul 21, 2009 |
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Preimplantation genetic diagnosis (PGD) has helped many couples conceive healthy children and is generally considered a safe practice. However, a new long-term analysis of PGD in mice suggests that this procedure may increase ...
Study identifies first molecular steps to childhood leukemia
Jul 15, 2009 |
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A Massachusetts General Hospital (MGH)-based research team has identified how a chromosomal abnormality known to be associated with acute lymphoblastic leukemia (ALL) - the most common cancer in children - initiates the disease ...
Scientists identify enzyme important in aging
Jul 10, 2009 |
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The secret to longevity may lie in an enzyme with the ability to promote a robust immune system into old age by maintaining the function of the thymus throughout life, according to researchers studying an "anti-aging" mouse ...
Single gene mutation responsible for 'catastrophic epilepsy'
Jul 07, 2009 |
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Catastrophic epilepsy - characterized by severe muscle spasms, persistent seizures, mental retardation and sometimes autism - results from a mutation in a single gene, said Baylor College of Medicine researchers in a report ...
Study pinpoints novel cancer gene and biomarker
Jun 24, 2009 |
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(PhysOrg.com) -- Dana-Farber Cancer Institute scientists' discovery of a cancer-causing gene - the first in its family to be linked to cancer - demonstrates how the panoramic view of genomics and the close-up ...
