News tagged with mre11
Protein complex key in avoiding DNA repair mistakes, cancer
As the body creates antibodies to fight invaders, a three-protein DNA repair complex called MRN is crucial for a normal gene-shuffling process to proceed properly, University of Michigan research shows.
Aug 05, 2009 |
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Protein's essential role in repairing damaged cells revealed
University of Michigan researchers have discovered that a key protein in cells plays a critical role in not one, but two processes affecting the development of cancer.
Biology /
Jan 06, 2009 |
3.3 / 5 (4) |
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New class of cancer drugs could work in colon cancers with genetic mutation, study finds
A class of drugs that shows promise in breast and ovarian cancers with BRCA gene mutations could potentially benefit colorectal cancer patients with a different genetic mutation, a new study from the University ...
Apr 25, 2011 |
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Structure of DNA repair complex reveals workings of powerful cell motor
(PhysOrg.com) -- Over the last years, two teams of researchers at The Scripps Research Institute have steadily built a model of how a powerful DNA repair complex works. Now, their latest discovery provides ...
Mar 27, 2011 |
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In the test tube, teams reconstruct a cancer cell's beginning
What prompts normal cells to transform themselves into cancerous cells? Researchers from Texas institutions, including the UT Health Science Center San Antonio, have identified factors in the very first step of the process ...
Nov 21, 2010 |
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Scientists find missing puzzle piece of powerful DNA repair complex
Researchers at The Scripps Research Institute have found, crystallized, and biologically characterized a poorly defined component of a key molecular complex that helps people to avoid cancer, but that also ...
Oct 01, 2009 |
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Study shows how defective DNA repair triggers 2 neurological diseases
Scientists at St. Jude Children's Research Hospital have teased apart the biological details distinguishing two related neurological diseases—ataxia telangiectasia-like disease (ATLD) and Nijmegen breakage syndrome (NBS).
Jan 15, 2009 |
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First glimpse of a key DNA repair protein at work
Repairing breaks in the two strands of the DNA double helix is critical for avoiding cancer. In humans and other organisms, a molecular machine called the MRN complex is responsible for finding and signaling ...
Biology /
Oct 03, 2008 |
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