News tagged with mrn


Protein's essential role in repairing damaged cells revealed

Protein's essential role in repairing damaged cells revealed

Biology /

created Jan 06, 2009 | popularity 3.3 / 5 (4) | comments 1

University of Michigan researchers have discovered that a key protein in cells plays a critical role in not one, but two processes affecting the development of cancer.





Search results for mrn


Protein complex key in avoiding DNA repair mistakes, cancer

Protein complex key in avoiding DNA repair mistakes, cancer

Biology / Cell & Microbiology

created Aug 05, 2009 | popularity 4.7 / 5 (3) | comments 0

As the body creates antibodies to fight invaders, a three-protein DNA repair complex called MRN is crucial for a normal gene-shuffling process to proceed properly, University of Michigan research shows.


Study shows how defective DNA repair triggers 2 neurological diseases

Medicine & Health / Genetics

created Jan 15, 2009 | popularity not rated yet | comments 0

Scientists at St. Jude Children's Research Hospital have teased apart the biological details distinguishing two related neurological diseases—ataxia telangiectasia-like disease (ATLD) and Nijmegen breakage syndrome (NBS).


Scientists decipher missing piece of first-responder DNA repair machine

Scientists find missing puzzle piece of powerful DNA repair complex

Biology / Cell & Microbiology

created Oct 01, 2009 | popularity 5 / 5 (6) | comments 0

Researchers at The Scripps Research Institute have found, crystallized, and biologically characterized a poorly defined component of a key molecular complex that helps people to avoid cancer, but that also ...


Mre11 Bound to DNA

First glimpse of a key DNA repair protein at work

Biology /

created Oct 03, 2008 | popularity 5 / 5 (13) | comments 0

Repairing breaks in the two strands of the DNA double helix is critical for avoiding cancer. In humans and other organisms, a molecular machine called the MRN complex is responsible for finding and signaling ...



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