News tagged with multiple myeloma
Powerful myeloma treatment regimen shows promise for AL amyloidosis
Two studies published today in Blood, the Journal of the American Society of Hematology (ASH), demonstrate preliminary success of an effective multiple myeloma (MM) regimen in patients with AL amyloidosis, a rare and devast ...
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Towards more effective treatment for multiple myeloma
A new study from SUNY Downstate Medical Center in Brooklyn, New York, shows that MAL3-101, a recently developed inhibitor of the heat shock protein 70 (Hsp70), appears to have potent anti-tumor effects on multiple myeloma, ...
Jan 09, 2012 |
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Peptide 'cocktail' elicits immune response to multiple myeloma
Scientists at Dana-Farber Cancer Institute have created a "cocktail" of immune-stimulating peptides they believe could provoke the body's defenses to attack multiple myeloma in its early "smoldering" phase and slow or prevent ...
Dec 13, 2011 |
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How patients will respond to immunomodulator therapy for multiple myeloma
Research on the same protein that was a primary mediator of the birth defects caused by thalidomide now holds hope in the battle against multiple myeloma, says the study's senior investigator, Keith Stewart, M.B., Ch.B. of ...
Dec 11, 2011 |
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Drug combination highly effective for newly diagnosed myeloma patients, study finds
(Medical Xpress) -- A three-drug combination treatment for the blood cancer multiple myeloma compares favorably to the best established therapy for newly diagnosed patients, according to a multi-center study led by Andrzej ...
Dec 08, 2011 |
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New class of drugs for the reversible inhibition of proteasomes
As the "recycling plant" of the cell, the proteasome regulates vitally important functions. When it is inhibited, the cell chokes on its own waste. Cancer cells, in particular, are very sensitive because they ...
Nov 22, 2011 |
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Scientists defeat hurdle to eradicating inactive multiple myeloma cells
Researchers at Virginia Commonwealth University Massey Cancer Center have developed a novel treatment strategy for multiple myeloma that delivers a deadly one-two blow to kill even the most inactive, or cytokinetically quiescent, ...
Nov 14, 2011 |
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Cancer drug may also work for scleroderma
A drug used to treat cancer may also be effective in diseases that cause scarring of the internal organs or skin, such as pulmonary fibrosis or scleroderma.
Medicine & Health / Medications
Sep 22, 2011 |
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Research examines over-the-counter drug's effect on chemo's side effects
New research has potential to alleviate the side effects of cancer treatments.
Sep 19, 2011 |
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Researchers use new tool to counter multiple myeloma drug resistance
Moffitt Cancer Center researchers, and colleagues, are pioneering promising research utilizing a monitoring technology that could provide a better understanding of acquired drug resistance and assist in clinical decision-making ...
Sep 09, 2011 |
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Novel approach scores first success against elusive cancer gene
Dana-Farber Cancer Institute scientists have successfully disrupted the function of a cancer gene involved in the formation of most human tumors by tampering with the gene's "on" switch and growth signals, rather than targeting ...
Sep 09, 2011 |
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Study urges caution with lenalidomide dosage
An early phase multiple myeloma trial has unexpectedly revealed that the drug lenalidomide interacts with another protein in cells that affect its dose level in the body, say researchers at the Ohio State University Comprehensive ...
Medicine & Health / Medications
Aug 08, 2011 |
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Growing up on livestock farm linked to increased risk of blood cancers
Growing up on a livestock farm seems to be linked to an increased risk of developing blood cancers as an adult, indicates research published online in Occupational and Environmental Medicine.
Jul 28, 2011 |
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In the lab and clinic, researchers develop a new therapy for blood cancers
Clinical researchers at VCU Massey Cancer Center have successfully completed a Phase I clinical trial evaluating a combination of the drugs Bortezomib and Alvocidib in patients with relapsed or refractory blood cancers, paving ...
Jun 02, 2011 |
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Researchers discover precisely how thalidomide causes birth defects
Thalidomide may have been withdrawn in the early 1960s for use by pregnant women, but its dramatic effects remain memorable half a century later. Now, researchers have taken a major step toward understanding exactly how thalidomide ...
Apr 19, 2011 |
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Multiple myeloma
Multiple myeloma (from myelo-, bone marrow), also known as MM, myeloma, plasma cell myeloma, or as Kahler's disease (after Otto Kahler) is a cancer of the white blood cells known as plasma cells, which produce antibodies.
These plasma cells, or B cells, are part of the immune system, formed in bone marrow, and numerous in lymphatics. Myeloma is incurable, but remissions may be induced with steroids, chemotherapy, thalidomide and stem cell transplants.
There were 15,270 cases diagnosed and 11,070 deaths in the United States in 2004, and an incidence of 4/100,000 worldwide. Median survival is 50–55 months. Chromosome diagnosis can separate patients into more or less favorable prognoses.
Myeloma is part of the broad group of diseases called hematological malignancies.
For more information about Multiple myeloma, read the full article at
Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.
