News tagged with muscular dystrophy
Need muscle for a tough spot? Turn to fat stem cells
(PhysOrg.com) -- Stem cells derived from fat have a surprising trick up their sleeves: Encouraged to develop on a stiff surface, they undergo a remarkable transformation toward becoming mature muscle cells. ...
Jan 27, 2012 |
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Research team discovers genes and disease mechanisms behind a common form of muscular dystrophy
Continuing a series of groundbreaking discoveries begun in 2010 about the genetic causes of the third most common form of inherited muscular dystrophy, an international team of researchers led by a scientist at Fred Hutchinson ...
Jan 12, 2012 |
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Study reveals enzyme function, could help find muscular dystrophy therapies
Researchers at the University of Iowa have worked out the exact function of an enzyme that is critical for normal muscle structure and is involved in several muscular dystrophies. The findings, which were published Jan. 6 ...
Jan 09, 2012 |
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A firmer understanding of muscle fibrosis
Researchers describe how increased production of a microRNA promotes progressive muscle deterioration in a mouse model of Duchenne muscular dystrophy (DMD), according to a study published online on January ...
Jan 02, 2012 |
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Some muscular dystrophy patients at increased risk for cancer
People who have the most common type of adult muscular dystrophy also have a higher risk of getting cancer, according to a paper published today in the Journal of the American Medical Association.
Dec 13, 2011 |
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Adult stem cells use special pathways to repair damaged muscle (w/ Video)
When a muscle is damaged, dormant adult stem cells called satellite cells are signaled to "wake up" and contribute to repairing the muscle. University of Missouri researchers recently found how even distant satellite cells ...
Dec 01, 2011 |
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Clinical trial for muscular dystrophy demonstrates safety of customized gene therapy
Researchers at the University of North Carolina at Chapel Hill have shown that it is safe to cut and paste together different viruses in an effort to create the ultimate vehicle for gene therapy. In a phase I clinical trial, ...
Nov 30, 2011 |
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Hope for muscle wasting disease
A health supplement used by bodybuilders could be the key to treating a life-threatening muscular dystrophy affecting hundreds of Australian children, new research shows.
Nov 22, 2011 |
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Stanford joins BrainGate team developing brain-computer interface to aid people with paralysis
(Medical Xpress) -- Stanford University researchers are enrolling participants in a pioneering study investigating the feasibility of people with paralysis using a technology that interfaces directly with ...
Medicine & Health / Neuroscience
Nov 14, 2011 |
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Scientists describe mechanism for rare muscle disease
(Medical Xpress) -- A team of scientists from the Friedrich Miescher Institute for Biomedical Research and the Hebrew University of Jerusalem describe in C. elegans the process leading to a rare form of Emery-Dreifuss ...
Oct 03, 2011 |
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Weakness in aging tied to leaky muscles
There is a reason exercise becomes more difficult with age. A report in the August Cell Metabolism, a Cell Press publication, ties the weakness of aging to leaky calcium channels inside muscle cells. But there is some good n ...
Aug 02, 2011 |
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Clinical trial of molecular therapy for muscular dystrophy yields significant positive results
A molecular technique originally developed at the University of North Carolina at Chapel Hill has taken one step closer to becoming a treatment for the devastating genetic disease Duchenne muscular dystrophy.
Jul 25, 2011 |
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First targeted treatment success for Duchenne Muscular Dystrophy
(Medical Xpress) -- A team led by scientists at UCL, funded by the Medical Research Council (MRC) and AVI BioPharma, have made an important breakthrough in the development of a treatment for Duchenne Muscular ...
Jul 25, 2011 |
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'Skipping' drug marks step forward for muscular dystrophy
An experimental drug designed to fit a DNA patch in a flawed gene has cleared an important hurdle in tests on boys struck by a tragic muscle-wasting disease, a British study on Monday says.
Jul 25, 2011 |
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Stem cell foundation for muscular dystrophy treatment
Research at the Australian Regenerative Medicine Institute (ARMI) at Monash University could lay the groundwork for new muscular dystrophy treatments.
Jul 14, 2011 |
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Muscular dystrophy
Muscular dystrophy (abbreviated MD) refers to a group of genetic, hereditary muscle diseases that weaken the muscles that move the human body. Muscular dystrophies are characterized by progressive skeletal muscle weakness, defects in muscle proteins, and the death of muscle cells and tissue. Nine diseases including Duchenne, Becker, limb girdle, congenital, facioscapulohumeral, myotonic, oculopharyngeal, distal, and Emery-Dreifuss are always classified as muscular dystrophy but there are more than 100 diseases in total with similarities to muscular dystrophy. Most types of MD are multi-system disorders with manifestations in body systems including the heart, gastrointestinal and nervous systems, endocrine glands, skin, eyes and other organs.
In the 1860s, descriptions of boys who grew progressively weaker, lost the ability to walk, and died at an early age became more prominent in medical journals. In the following decade, French neurologist Guillaume Duchenne gave a comprehensive account of 13 boys with the most common and severe form of the disease (which now carries his name — Duchenne muscular dystrophy). It soon became evident that the disease had more than one form, and that these diseases affected males of all ages.[citation needed]
For more information about Muscular dystrophy, read the full article at
Wikipedia.
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