News tagged with mutant lines
200,000 rice mutants available worldwide for scientific investigation
Mar 04, 2009 |
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Scientists across the world are building an extensive repository of genetically modified rice plants in the hope of understanding the function of the approximately 57,000 genes that make up the genome of Oryza sativa. The ...
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Chemopreventive isothiocyanates selectively depletes mutant p53 in tumor cells
Apr 20, 2009 |
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Researchers at Lombardi Comprehensive Cancer Center at Georgetown University Medical Center have demonstrated that naturally-occurring compounds can selectively deplete mutant p53 and restore "wild type" function to p53 in ...
Calcium aids protein folding as therapy for enzymes in types of lysosomal storage diseases
Biology /
Feb 05, 2008 |
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Lysosomes are organelles that break down macromolecules in a cell, and this process is crucial for maintaining healthy cells. A lysosomal storage disease results from deficient activity of the hydrolytic enzymes, responsible ...
Lamin B locks up Oct-1
Biology /
Jan 12, 2009 |
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A large fraction of the transcription factor Oct-1 is associated with the inner nuclear envelope, but how and why it is retained there was unknown.
Study a step toward disease-resistant crops, sustainability
Biology /
Nov 12, 2008 |
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A five-year study that could help increase disease resistance, stress tolerance and plant yields is under way at Purdue University.
Scientists identify gene that may contribute to improved rice yield
Biology /
Sep 28, 2008 |
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A team of scientists, including Penn State Distinguished Professor of Biology Hong Ma, has identified a gene in rice that controls the size and weight of rice grains. The gene may prove to be useful for breeding ...
2 heads are better than 1: 2 dysfunctional DNA repair pathways kill tumor cells
Apr 13, 2007 |
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Individuals who inherit two mutant copies of any one of about 12 genes that make the proteins of the Fanconi Anemia (FA) pathway develop FA, which is characterized by increased incidence of cancer and bone marrow failure, ...
Researchers identify proteins making up mechanosensitive ion channels
Biology /
Jun 02, 2008 |
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Researchers at Washington University in St. Louis are the first to identify two proteins responsible for mechanosensitive ion channel activities in plant roots. Scientists have long known that plant cells respond to physical ...
Scientists discover soy component may be key to fighting colon cancer
Nov 24, 2009 |
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A study conducted by Children's Hospital & Research Center Oakland scientists identifies a new class of therapeutic agents found naturally in soy that can prevent and possibly treat colon cancer, the third most deadly form ...
Team finds an economical way to boost the vitamin A content of maize
Biology /
Jan 17, 2008 |
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A team of plant geneticists and crop scientists has pioneered an economical approach to the selective breeding of maize that can boost levels of provitamin A, the precursors that are converted to vitamin A ...
Revealing cancers' weak spots: Researchers exploit genetic 'co-dependence' to kill treatment-resistant tumor cells
Oct 20, 2009 |
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(PhysOrg.com) -- Cancer cells fueled by the mutant KRAS oncogene, which makes them notoriously difficult to treat, can be killed by blocking a more vulnerable genetic partner of KRAS, report scientists at ...
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