News tagged with mutant mice
New function for the protein Bcl-xL: It prevents bone breakdown
Sep 14, 2009 |
5 / 5 (1) |
0
In blood cells, the protein Bcl-xL has a well-characterized role in preventing cell death by a process known as apoptosis. However, its function(s) in osteoclasts, cells that slowly breakdown bone (a process known as resorption), ...
Scientists create entirely new way to study brain function
Medicine & Health / Neuroscience
Jul 15, 2009 |
4.7 / 5 (3) |
1
(PhysOrg.com) -- Scientists at Duke University and the University of North Carolina have devised a chemical technique that promises to allow neuroscientists to discover the function of any population of neurons in an animal ...
No helicopter moms among Rutgers mutant mice
Biology /
Sep 15, 2008 |
4 / 5 (4) |
0
First, he discovered a gene that controls innate fear in animals. Now Rutgers geneticist Gleb Shumyatsky has shown that the same gene promotes "helicopter mom" behavior in mice. The gene, known as stathmin or oncoprotein ...
Search results for mutant mice
The key to survival and virulence for a fungal pathogen is autophagy
Feb 08, 2008 |
not rated yet |
0
Autophagy is a process whereby cells recycle material during stress situations, such as when nutrients are scarce. Some cells also use this process as an immune defense mechanism to eliminate pathogens. However, new data, ...
Stabilizing cancer-fighting p53 can also shield a metastasis-promoter
May 22, 2008 |
4 / 5 (2) |
1
Efforts to protect the tumor-suppressor p53 could just as easily shelter a mutant version of the protein, causing cancer cells to thrive and spread rather than die, according to research by scientists at The University of ...
Blind mice shed light on human sight loss
Nov 22, 2007 |
4 / 5 (2) |
0
Mutant mice could provide genetic clues to understanding incurable human sight loss resulting from retinal degeneration. Research published in the online open access journal Genome Biology uncovers a role for microRNA in ret ...
'Intrabody' can mop up mutant protein in Huntington's disease model
May 26, 2008 |
4.8 / 5 (5) |
0
Scientists have created a tool for mopping up the clumps of mutant protein that drive neurodegeneration in Huntington's disease. Emory University researchers engineered a virus to make an intracellular antibody or "intrabody" ...
Mighty mice: Treatment targeted to muscle improves motor neuron disease
Medicine & Health / Neuroscience
Aug 12, 2009 |
not rated yet |
0
New research with transgenic mice reveals that a therapy directed at the muscle significantly improves disease symptoms of a genetic disorder characterized by destruction of the neurons that control movement. The study, published ...
New mouse mutant contains clue to progressive hearing loss
Biology /
Oct 31, 2008 |
not rated yet |
0
Researchers have defined a mutation in the mouse genome that mimics progressive hearing loss in humans. A team from the Wellcome Trust Sanger Institute in Cambridge, UK, working with colleagues in Munich and Padua, found ...
Mutant proteins result in infectious prion disease in mice
Biology /
Dec 05, 2008 |
5 / 5 (1) |
0
A worldwide group of scientists has created an infectious prion disease in a mouse model, in a step that may help unravel the mystery of this progressive disease that affects the nervous system in humans and animals. The ...
Effect of mutant p53 stability on tumorigenesis and drug design
May 15, 2008 |
4.5 / 5 (2) |
0
In the May 15th issue of G&D, Dr. Guillermina Lozano (MD Anderson Cancer Center) and colleagues reveal how the stabilization of a mutated form of p53 affects oncogenesis, and lends startling new insight into the potential ...
2 drugs are better than 1 at targeting tumors with B-RAF mutations
Oct 24, 2008 |
5 / 5 (1) |
0
In a proportion of human solid tumors, in particular melanomas (a form of skin cancer that is often resistant to chemotherapy), inappropriate activation of the MEK/ERK signaling pathway as a result of mutations in the B-RAF ...
Gene mutations in mice mimic human-like sleep disorder, researchers find
May 20, 2008 |
4.5 / 5 (2) |
0
DALLAS – May 20, 2008 – Mutations in two genes that control electrical excitability in a portion of the brain involved in sleep create a human-like insomnia disorder in mice, UT Southwestern Medical Center researchers have ...
List of search results for mutant mice
