News tagged with mutant protein
Mighty mice: Treatment targeted to muscle improves motor neuron disease
Medicine & Health / Neuroscience
Aug 12, 2009 |
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New research with transgenic mice reveals that a therapy directed at the muscle significantly improves disease symptoms of a genetic disorder characterized by destruction of the neurons that control movement. The study, published ...
Modification of mutant huntingtin protein increases its clearance from brain cells
Apr 02, 2009 |
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A new study has identified a potential strategy for removing the abnormal protein that causes Huntington's disease (HD) from brain cells, which could slow the progression of the devastating neurological disorder. In the ...
Just a little squeeze lets proteins assess DNA
Biology /
Dec 16, 2008 |
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(PhysOrg.com) -- To find its target, all a protein needs to do is give quick squeezes as it moves along the DNA strand, suggests new research from The University of Arizona in Tucson.
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Mutant host cell protein sequesters critical HIV-1 element
Medicine & Health / HIV & AIDS
Jan 15, 2009 |
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Scientists have identified a new way to inhibit a molecule that is critical for HIV pathogenesis. The research, published by Cell Press in the January 16th issue of the journal Molecular Cell, presents a target for develo ...
Chemopreventive isothiocyanates selectively depletes mutant p53 in tumor cells
Apr 20, 2009 |
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Researchers at Lombardi Comprehensive Cancer Center at Georgetown University Medical Center have demonstrated that naturally-occurring compounds can selectively deplete mutant p53 and restore "wild type" function to p53 in ...
Researchers identify new, cancer-causing role for protein
Aug 27, 2009 |
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The mainstay immune system protein TRAF6 plays an unexpected, key role activating a cell signaling molecule that in mutant form is associated with cancer growth, researchers at The University of Texas M. D. ...
Subtle change dramatically reduces pathogenic potential of Huntington's protein
Dec 23, 2009 |
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Scientists have identified a key molecular switch that may drive the onset of Huntington's disease (HD), an incurable neurodegenerative disorder that leads to severe disruptions in muscle coordination and cognitive function. ...
Mutant proteins result in infectious prion disease in mice
Biology /
Dec 05, 2008 |
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A worldwide group of scientists has created an infectious prion disease in a mouse model, in a step that may help unravel the mystery of this progressive disease that affects the nervous system in humans and animals. The ...
Generation of a severe memory-deficit mutant mouse by exclusively eliminating the kinase activity of CaMKIIalpha
Medicine & Health / Neuroscience
Jun 19, 2009 |
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A Japanese research group, led by Dr. Yoko Yamagata of the National Institute for Physiological Sciences, has successfully generated a novel kinase-dead mutant mouse of the CaMKIIalpha gene that completely and exclusively ...
Promising new treatment for Alzheimer's suggested
Jul 20, 2009 |
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Research carried out at the Hebrew University of Jerusalem has resulted in a promising approach to help treat Alzheimer's disease in a significant proportion of the population that suffers from a particularly rapid development ...
Mutant gene's true effect revealed - giving new therapy hope
Oct 19, 2009 |
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(PhysOrg.com) -- Scientists have revealed how a mutant gene that causes a connective tissue disease resulting in dwarfism does so by significantly affecting the inside of cells - opening up new therapy strategies that involve ...
Model for angelman syndrome developed
Aug 14, 2008 |
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A model for studying the genetics of Angelman syndrome, a neurological disorder that causes mental retardation and other symptoms in one out of 15,000 births, has been developed by biologists at The University of Texas at ...
New hope for treatment of neurodegenerative disorder
Apr 20, 2009 |
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Researchers from the University of Southern California have taken an important first step toward protecting against Huntington disease using gene therapy.
List of search results for mutant protein
