News tagged with mutated genes
'Smothered' genes combine with mutations to yield poor outcome in cancer patients
Jul 15, 2008 |
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Johns Hopkins Kimmel Cancer Center researchers have identified a set of genes in breast and colon cancers with a deadly combination of traditional mutations and "smothered" gene activity that may result in poor outcomes for ...
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A new method to identify mutated genes in human diseases
Biology /
Mar 28, 2008 |
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Researchers from the University of Turin, Italy and the University of Nijmegen, The Netherlands, have devised a new method that may help the medical community to determine the genetic basis of many common diseases. Their ...
Two genes cooperate to cause aggressive leukemia
Nov 03, 2009 |
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Two genes, each one of which is known to cause cancer on its own, together can lead to aggressive leukaemia. This is the conclusion from new research carried out on gene-modified mice at the Sahlgrenska Academy at the University ...
Tumor mutations can predict chemo success
Aug 06, 2009 |
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(PhysOrg.com) -- New work by MIT cancer biologists shows that the interplay between two key genes that are often defective in tumors determines how cancer cells respond to chemotherapy.
Protein-protein interaction explains vision loss in genetic diseases
May 10, 2009 |
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The mystery of genetic disease is only partially solved with the identification of a mutated gene. Often, the pattern of disease - the features or disorders associated with it - vary in type and severity among those who are ...
Survival of the fittest: even cancer cells follow the laws of evolution
Biology /
Aug 01, 2008 |
4.6 / 5 (14) |
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Scientists from The Institute of Advanced Studies at Princeton and the University of California discovered that the underlying process in tumor formation is the same as for life itself—evolution. After analyzing a half million ...
Researchers Identify New Protein Important in Breast Cancer Gene's Role in DNA Repair
Mar 17, 2009 |
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(PhysOrg.com) -- For years, researchers have known that under normal conditions, the breast cancer protein BRCA1 orchestrates the repair of damaged DNA, but the details of just how BRCA1 moves to the damaged ...
Variant form of amyloid beta hinders amyloidogenesis, development of Alzheimer's disease
Medicine & Health / Neuroscience
Mar 12, 2009 |
4 / 5 (1) |
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Alzheimer's disease causes misfolding and aggregation of a protein fragment known as amyloid beta and its deposition as plaques in the brain. This process triggers a cascade of event that leads to neurodegeneration. A new ...
Researchers discover gene mutations that cause childhood brain cancer
Mar 08, 2009 |
4 / 5 (1) |
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Researchers funded by the Canadian Cancer Society have discovered eight similar genes that, when mutated, appear to be responsible for medulloblastoma - the most common of childhood brain cancers. The findings are published ...
Genetic based human diseases are an ancient evolutionary legacy
Biology /
Oct 16, 2008 |
4.7 / 5 (7) |
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Tomislav Domazet-Lošo and Diethard Tautz from the Max Planck Institute for Evolutionary Biology in Plön, Germany, have systematically analysed the time of emergence for a large number of genes - genes which ...
A new discovered mutation can hold the key to treat a large number of different cancers
Feb 17, 2009 |
5 / 5 (2) |
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Scientists have discovered a mutation responsible for cancer progression, a finding with potential implications for the development of treatment against not one, but a series of cancer types since this mutation can be linked ...
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