News tagged with national cancer institute


Melanosome dynamics and sensitivity of melanoma cells to chemotherapy

Medicine & Health / Cancer

created Aug 25, 2009 | popularity not rated yet | comments 0

Manipulating the functions of melanosomes--the organelles in pigment-producing cells--may enhance the activity of anticancer drugs used against melanoma, according to a new study published online August 24 in the Journal of ...


Surgeon training found effective in breast cancer sentinel lymph node trial

Medicine & Health / Cancer

created Aug 24, 2009 | popularity not rated yet | comments 0

Training methods for surgeons who perform breast cancer sentinel lymph node resection were found to be effective in almost 97% of surgeons assessed, according to a new study published online August 24 in the Journal of th ...


Fecal DNA methylation detects gastric and colorectal cancers

Medicine & Health / Cancer

created Aug 21, 2009 | popularity 5 / 5 (1) | comments 0

A preliminary evaluation of methylation of two gene promoters in fecal DNA showed promise as a noninvasive method to detect colorectal and gastric cancers, according to a new study published online August 21 in the Journal of ...


The public overestimates benefits of cancer screening, survey finds

Medicine & Health / Cancer

created Aug 11, 2009 | popularity not rated yet | comments 1

A public survey conducted in Europe found that the vast majority of people overestimate the life-saving benefits of breast and prostate cancer screening, according to a new study published online August 12 in the Journal of ...


Cost-effectiveness of cetuximab in metastatic colorectal cancer

Medicine & Health / Cancer

created Aug 08, 2009 | popularity not rated yet | comments 0

From a health-care system perspective, it may be more efficient to use the drug cetuximab only in colorectal cancer patients whose tumors have a wild-type KRAS gene, according to a study published online August 7 in the Journal of ...


Considering combination versus sequential chemotherapy in metastatic breast cancer

Medicine & Health / Cancer

created Aug 05, 2009 | popularity not rated yet | comments 0

Both combination and sequential single-agent chemotherapy are reasonable options to treat metastatic breast cancer, but the choice between the two should ultimately be based on patient- and disease-related factors, according ...


AIDS patients face higher risk of HPV-related cancers as immunosuppression grows

Medicine & Health / Cancer

created Jul 31, 2009 | popularity not rated yet | comments 0

Risk of human papillomavirus (HPV)-associated cancers is greater for people living with AIDS and increases with increasing immunosuppression, according to a new study published online July 31 in the Journal of the National Ca ...


EphA2-targeted therapy delivers chemo directly to ovarian cancer cells

Medicine & Health / Cancer

created Jul 29, 2009 | popularity not rated yet | comments 0

With a novel therapeutic delivery system, a research team led by scientists at The University of Texas M. D. Anderson Cancer Center has successfully targeted a protein that is over-expressed in ovarian cancer cells. Using ...


Older cancer patients have more frailty than other seniors

Medicine & Health / Cancer

created Jul 29, 2009 | popularity not rated yet | comments 0

Older people with a history of cancer are more likely to have disabilities and be frail and vulnerable than older adults who have not had cancer, according to a study in the Journal of the National Cancer Institute, publis ...


Thalidomide does not improve survival in small cell lung cancer

Medicine & Health / Cancer

created Jul 16, 2009 | popularity not rated yet | comments 0

Treating patients with thalidomide in combination with chemotherapy for small cell lung cancer (SCLC) did not improve their survival but did increase their risk of blood clots, according to a new study published online July ...


Why are African-Americans less likely to survive certain cancers?

Medicine & Health / Cancer

created Jul 07, 2009 | popularity not rated yet | comments 3

African Americans are more likely than other races to die from breast, prostate and ovarian cancers, but this disparity is not due to poverty or inferior healthcare, a first-of-its-kind study has found.


Improving the biomarker pipeline for early cancer detection

Medicine & Health / Cancer

created Jul 02, 2009 | popularity not rated yet | comments 1

Several statistical and biological issues need to be addressed in order to improve biomarker identification for early detection of cancer, according to a commentary published online July 2 in the Journal of the National Ca ...


Risk of breast cancer and a single-nucleotide polymorphism

Medicine & Health / Cancer

created Jul 02, 2009 | popularity not rated yet | comments 0

The single-nucleotide polymorphism (SNP) known as 2q35-rs13387042 is associated with increased risk of estrogen receptor (ER) -positive and -negative breast cancer, according to a study published online July 1 in the Journal of ...


Cost-effectiveness of HPV vaccination in the Netherlands

Medicine & Health / Cancer

created Jul 01, 2009 | popularity not rated yet | comments 0

Even under favorable assumptions, including lifelong protection against 70% of all cervical cancers and no side effects, vaccination against the human papillomavirus (HPV) is not cost-effective in the Netherlands, according ...


How much is life worth? The $440 billion question

Medicine & Health / Cancer

created Jun 29, 2009 | popularity 5 / 5 (1) | comments 2

The decision to use expensive cancer therapies that typically produce only a relatively short extension of survival is a serious ethical dilemma in the U.S. that needs to be addressed by the oncology community, according ...