News tagged with national cancer
Long-term testicular cancer survivors at high risk for neurological side effects
Nov 25, 2009 |
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Long-term survivors of testicular cancer who were treated with cisplatin-based chemotherapy had more severe side effects, including neurological side effects and Raynaud-like phenomena, than men who were not treated with ...
Estrogen receptor-alpha, breast cancer patients and tamoxifen response
Nov 25, 2009 |
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Researchers have found evidence of a statistically significant survival benefit from adjuvant tamoxifen among patients whose estrogen receptor (ER)-positive tumors had high levels of phosphorylation of ER-alpha; at serine-118 ...
Cancer patients and doctors report drug side effects differently
Nov 17, 2009 |
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In clinical trials for cancer, it is standard for clinicians rather than patients to report adverse symptom side effects from treatments, such as nausea and fatigue. At present, patient self-reporting, although important, ...
Bladder cancer risks increase over time for smokers
Nov 16, 2009 |
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Risk of bladder cancer for smokers has increased since the mid-1990s, with a risk progressively increasing to a level five times higher among current smokers in New Hampshire than that among nonsmokers in 2001-2004, according ...
Antitumor activity of nutlin-3 in neuroblastoma with wild-type p53
Nov 10, 2009 |
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The small-molecule inhibitor nutlin-3 may be a viable treatment option for neuroblastoma patients with wild-type p53 activity, according to a new study published online November 10 in the Journal of the National Cancer In ...
Drugs to treat anemia in cancer patients linked to thromboembolism
Nov 10, 2009 |
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Medications frequently given to cancer patients to reduce their risk of anemia are associated with an increased risk of deep vein thrombosis or pulmonary embolism, according to new research led by Dawn Hershman, M.D, M.S., ...
Age-specific evaluation of HPV DNA testing vs. cytology screening
Nov 10, 2009 |
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Human papillomavirus (HPV) DNA testing with cytology triage is more sensitive than conventional cytology screening for detecting cervical lesions, according to a new study published online November 9 in the Journal of th ...
Detecting overall survival benefit derived from progression-free survival
Nov 10, 2009 |
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Overall survival (OS) may be a reasonable primary endpoint when the median survival postprogession (SSP) is less than 6 months, but it is too high a hurdle when SPP is longer than 12 months, according to a new study published ...
Higher incidence of thyroid cancer in volcanic area of Sicily
Nov 05, 2009 |
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People living in volcanic areas may be at a higher risk for thyroid cancer, according to a new study published online November 5 in the Journal of the National Cancer Institute.
Breast cancer incidence in Spain drops in early 2000s after decades of increasing rates
Oct 26, 2009 |
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After a steady increase of invasive breast cancer cases in Spanish women during the 1980s and 1990s, incidence rates abruptly declined starting in 2001—a trend most likely explained by a period effect linked to screening ...
Holocaust survivors at higher risk for all cancers
Oct 26, 2009 |
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Jewish survivors of World War II who were potentially exposed to the Holocaust are at a higher risk for cancer occurrence, according to a new study published online October 26 in the Journal of the National Cancer Institute.
Using relative utility curves for risk prediction
Oct 20, 2009 |
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A relative utility curve is a simple method to evaluate risk prediction in a medical decision-making framework, according to a commentary published online October 20 in the Journal of the National Cancer Institute.
Effects of aspirin and folic acid on inflammation markers for colorectal adenomas
Oct 12, 2009 |
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Unexpectedly, inflammation markers do not appear to be involved with the chemopreventative effect of aspirin on colorectal adenomas, according to a brief communication published online October 12 in the Journal of the Na ...
Teen smoking-cessation trial first to achieve significant quit rates
Oct 12, 2009 |
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For the first time, researchers at Fred Hutchinson Cancer Research Center have demonstrated that it is possible to successfully recruit and retain a large number of adolescent smokers from the general population into a smoking ...
Increased levels of Muellerian-inhibiting substance could mean greater breast cancer risk
Oct 09, 2009 |
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Women with increased levels of Müllerian inhibiting substance (MIS), best known for regulating in utero sexual differentiation in boys, may be at a greater risk for breast cancer, according to a new study published online ...


