News tagged with nature structural and molecular biology

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Researchers describe molecular 'two-step' leading to protein clumps of Huntington's disease

Biology / Cell & Microbiology

created Mar 08, 2009 | popularity not rated yet | comments 0

In a paper published in the early online version of Nature Structural and Molecular Biology, researchers at the University of Pittsburgh School of Medicine deconstruct the first steps in an intricate molecular dance that m ...


Scientists identify human monoclonal antibodies effective against bird and seasonal flu viruses

Biology /

created Feb 22, 2009 | popularity 5 / 5 (7) | comments 1

Researchers at the Dana-Farber Cancer Institute, Burnham Institute for Medical Research and the Centers for Disease Control and Prevention have reported the identification of human monoclonal antibodies (mAb) that neutralize ...


Protein complex key in avoiding DNA repair mistakes, cancer

Protein complex key in avoiding DNA repair mistakes, cancer

Biology / Cell & Microbiology

created Aug 05, 2009 | popularity 4.7 / 5 (3) | comments 0

As the body creates antibodies to fight invaders, a three-protein DNA repair complex called MRN is crucial for a normal gene-shuffling process to proceed properly, University of Michigan research shows.


Scientists clarify editing error underlying genetic neurodegenerative disease

Biology /

created Jan 28, 2009 | popularity 5 / 5 (2) | comments 0

Two molecular biologists at Cold Spring Harbor Laboratory have uncovered important new details about how a gene mutation causes a cellular editing error that results in a devastating disease called pontocerebellar hypoplasia ...


Biologists discover link between CGG repeats in DNA and neurological disorders

Biology /

created Jan 11, 2009 | popularity 5 / 5 (2) | comments 0

Researchers have long known that some repetitive DNA sequences can make human chromosomes "fragile," i.e. appearing constricted or even broken during cell divisions. Scientists at Tufts University have found that one such ...


Raising the alarm when DNA goes bad (w/ Video)

Biology / Cell & Microbiology

created Aug 13, 2009 | popularity 2 / 5 (1) | comments 1

Scientists have known for a long time that when DNA is damaged, a key enzyme sets off a cellular "alarm bell" to alert the cell to start the repair process, but until recently little was known about how the cell detects and ...


Researchers 'unzip' molecules to measure interactions keeping DNA packed in cells

Researchers 'unzip' molecules to measure interactions keeping DNA packed in cells

Biology /

created Jan 28, 2009 | popularity 4 / 5 (1) | comments 0

(PhysOrg.com) -- Anyone who has ever battled a stuck zipper knows it's a good idea to see what's stuck, where and how badly -- and then to pull hard. A Cornell research team's experiments involve the "unzipping" ...