Video: Repeat expansion disorders—how RNA may gum up the works
What happens when an RNA molecule contains too many repeats of the same short sequence of bases, or RNA building blocks?
What happens when an RNA molecule contains too many repeats of the same short sequence of bases, or RNA building blocks?
Molecular & Computational biology
Apr 5, 2023
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Very low concentrations of the popular organic insecticide spinosad have profound effects on beneficial insect species, including vision loss and neurodegeneration, new research led by the University of Melbourne has found.
Plants & Animals
Feb 24, 2022
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The connections are still obscure, but mounting evidence points to a link between infections, the immune system, and neurodegenerative diseases like Alzheimer's, ALS, and Parkinson's.
Biochemistry
Nov 23, 2015
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(Phys.org) —Proteins, unlike diamonds, aren't forever. And when they wear out, they need to be degraded in the cell back into amino acids, where they will be recycled into new proteins. Researchers at Rockefeller University ...
Cell & Microbiology
Apr 26, 2013
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The University of Manchester is leading the way when it comes to fly research with the publication of the first ever basic training package to teach students and scientists how to best use the fruit fly, Drosophila, for research. ...
Plants & Animals
Feb 13, 2013
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How the intricate network of blood vessels forms within the brain has long fascinated biologists. Though the human brain comprises only 2 percent of body weight it receives up to 15 percent of the cardiac output through this ...
Plants & Animals
Aug 14, 2012
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Alzheimer's disease is triggered by the inappropriate processing of amyloid precursor protein to generate excess amounts of short peptide fragments called A-beta. For many years, the neurodegeneration associated with Alzheimer's ...
Cell & Microbiology
Oct 24, 2011
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Mapping the fat distribution of the healthy human brain is a key step in understanding neurological diseases, in general, and the neurodegeneration that accompanies Alzheimer's disease in particular. Antonio Veloso and colleagues, ...
Analytical Chemistry
May 4, 2011
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Patients with Parkinson's disease (PD) suffer a specific loss of dopaminergic neurons from the midbrain region that controls motor function. The exact mechanism of this selective neurodegeneration is unclear, though many ...
Cell & Microbiology
Mar 7, 2011
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Neurodegeneration is the umbrella term for the progressive loss of structure or function of neurons, including death of neurons. Many neurodegenerative diseases including Parkinson’s, Alzheimer’s, and Huntington’s occur as a result of neurodegenerative processes. As research progresses, many similarities appear which relate these diseases to one another on a sub-cellular level. Discovering these similarities offers hope for therapeutic advances that could ameliorate many diseases simultaneously. There are many parallels between different neurodegenerative disorders including atypical protein assemblies as well as induced cell death. Neurodegeneration can be found in many different levels of neuronal circuitry ranging from molecular to systemic.
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