Rhomboid proteases are a promising target for new drugs. Now researchers from the Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) have uncovered a mechanism for regulating enzyme activity. The key role is played ...
Cell & Microbiology
Jul 21, 2023
0
48
What causes certain individuals who experience a sudden decline in kidney function to develop kidney disease while others recover? A new study co-led by bioengineers at the University of California San Diego could provide ...
Cell & Microbiology
Jul 19, 2023
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3
The World Health Organization lists bacteria that are resistant to antibiotics as one of the top 10 global health threats. Therefore, researchers are looking for new antibiotics to counter this resistance. Adéla Melcrová, ...
Cell & Microbiology
Jul 13, 2023
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12
A team of scientists from around the globe, including those from Trinity College Dublin, has gained high-res structural insights into a key bacterial enzyme that may help chemists design new drugs to inhibit it and thus suppress ...
Biochemistry
Jun 30, 2023
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52
A screening technique commonly used in drug discovery can yield important details about the actions of molecular 'glues' in protein interactions.
Biochemistry
Jun 8, 2023
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8
A new "molecular editing" technique from Scripps Research enables chemists to add new elements to organic molecules at locations that were previously out of reach.
Analytical Chemistry
May 31, 2023
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14
Scientists at McMaster University and the Massachusetts Institute of Technology have used artificial intelligence to discover a new antibiotic that could be used to fight a deadly, drug-resistant pathogen that strikes vulnerable ...
Biochemistry
May 25, 2023
0
105
Scientists have long been challenged by the complex process of drug discovery and development, with investments that often go unrewarded. However, with the advancement of experimental technology and computer hardware, artificial ...
Analytical Chemistry
May 22, 2023
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37
Chemotherapy that does not harm the body, but effectively fights cancer cells: that is the goal of chemist Sylvestre Bonnet and his team. During his Ph.D. research, chemist Xuequan Zhou brought that goal a little closer. ...
Bio & Medicine
May 12, 2023
0
113
A method to store advanced cell models has been developed by researchers at the University of Warwick.
Biochemistry
May 2, 2023
0
154
