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Nicotine

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Nicotine is an alkaloid found in the nightshade family of plants (Solanaceae) which constitutes approximately 0.6–3.0% of dry weight of tobacco, with biosynthesis taking place in the roots, and accumulating in the leaves. It functions as an antiherbivore chemical with particular specificity to insects; therefore nicotine was widely used as an insecticide in the past, and currently nicotine analogs such as imidacloprid continue to be widely used.

In low concentrations (an average cigarette yields about 1 mg of absorbed nicotine), the substance acts as a stimulant in mammals and is one of the main factors responsible for the dependence-forming properties of tobacco smoking. According to the American Heart Association, "Nicotine addiction has historically been one of the hardest addictions to break." The pharmacological and behavioral characteristics that determine tobacco addiction are similar to those that determine addiction to drugs such as heroin and cocaine. Nicotine content in cigarettes has actually slowly increased over the years, and one study found that there was an average increase of 1.6% per year between the years of 1998 and 2005. This was found for all major market categories of cigarettes.

For more information about Nicotine, read the full article at Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.


News tagged with nicotine

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smoking, cigarette

Vaccine being developed to help smokers quit

Medicine & Health / Medications

created Nov 20, 2009 | popularity 4.3 / 5 (15) | comments 10

(PhysOrg.com) -- Glaxo-SmithKline has joined forces with Nabi Pharmaceuticals to produce a vaccine to help smokers give up their addiction permanently.


How cigarettes calm you down

Medicine & Health / Research

created Apr 24, 2009 | popularity 4.8 / 5 (9) | comments 0

The calming neurological effects of nicotine have been demonstrated in a group of non-smokers during anger provocation. Researchers writing in BioMed Central's open access journal Behavioral and Brain Functions suggest that n ...


Crushing cigarettes in a virtual reality environment reduces tobacco addiction

Medicine & Health / Psychology & Psychiatry

created Oct 27, 2009 | popularity not rated yet | comments 0

Smokers who crushed computer-simulated cigarettes as part of a psychosocial treatment program in a virtual reality environment had significantly reduced nicotine dependence and higher rates of tobacco abstinence than smokers ...


Scientists seek to manage dopamine's good and bad sides

Medicine & Health / Research

created Oct 07, 2009 | popularity 5 / 5 (6) | comments 0

The good, the bad and the ugly: That's a quick summary of the effects of dopamine, a natural brain chemical that's linked to pleasure, addiction and disease.


Cocaine Vaccine Shows Promise for Treating Addiction

Medicine & Health / Research

created Oct 05, 2009 | popularity 5 / 5 (3) | comments 5

(PhysOrg.com) -- Immunization with an experimental anti-cocaine vaccine resulted in a substantial reduction in cocaine use in 38 percent of vaccinated patients in a clinical trial supported by the National Institute on Drug ...


Learning addiction: Dopamine reinforces drug-associated memories

Medicine & Health / Neuroscience

created Sep 09, 2009 | popularity 5 / 5 (1) | comments 0

New research with mice has provided some fascinating insight into how addictive drugs hijack reward signals and influence neural processes associated with learning and memory. The research, published by Cell Press in the ...


Simple drug treatment may prevent nicotine-induced SIDS

Simple drug treatment may prevent nicotine-induced SIDS

Medicine & Health / Neuroscience

created Jun 03, 2009 | popularity not rated yet | comments 1

(PhysOrg.com) -- A new study has identified a specific class of pharmaceutical drugs that could be effective in treating babies vulnerable to Sudden Infant Death Syndrome (SIDS), because their mothers smoked ...


Skin color clue to nicotine dependence

Medicine & Health / Research

created May 08, 2009 | popularity 5 / 5 (2) | comments 0

Higher concentrations of melanin -- the color pigment in skin and hair -- may be placing darker pigmented smokers at increased susceptibility to nicotine dependence and tobacco-related carcinogens than lighter skinned smokers, ...


Nicotine may have more profound impact than previously thought

Nicotine may have more profound impact than previously thought

Medicine & Health / Research

created Apr 03, 2009 | popularity 4.6 / 5 (7) | comments 3

Nicotine isn't just addictive. It may also interfere with dozens of cellular interactions in the body, new Brown University research suggests.


Tobacco regulation bill up for vote Thursday (AP)

House approves FDA regulation of tobacco products

Medicine & Health / Health

created Apr 02, 2009 | popularity 3 / 5 (2) | comments 0

(AP) -- The federal government would for the first time have regulatory powers over the tobacco industry under a bill the House approved Thursday after years of campaigning by anti-smoking forces.


Caltech researchers find tiny genetic change keeps nicotine from binding to muscle cells

Researchers find tiny genetic change keeps nicotine from binding to muscle cells

Chemistry / Biochemistry

created Mar 23, 2009 | popularity 5 / 5 (1) | comments 0

A tiny genetic mutation is the key to understanding why nicotine--which binds to brain receptors with such addictive potency--is virtually powerless in muscle cells that are studded with the same type of receptor. ...


Nicotine Activates More than Just the Brain’s Pleasure Pathways

Medicine & Health / Research

created Jan 26, 2009 | popularity 3.7 / 5 (3) | comments 0

(PhysOrg.com) -- Duke University Medical System researchers have discovered there are differing taste pathways for nicotine, which could provide a new approach for future smoking-cessation products.


Nicotine activates more than just the brain's pleasure pathways

Medicine & Health / Research

created Jan 22, 2009 | popularity 4 / 5 (4) | comments 0

Duke University Medical System researchers have discovered there are differing taste pathways for nicotine, which could provide a new approach for future smoking-cessation products.


Genetic markers identified for alcohol response

Medicine & Health / Genetics

created Dec 09, 2008 | popularity 5 / 5 (1) | comments 0

Researchers at the UCSF Ernest Gallo Clinic and Research Center have identified a region on the human genome that appears to determine how strongly drinkers feel the effects of alcohol and thus how prone they are to alcohol ...


Scientists find blocking a neuropeptide receptor decreases nicotine addiction

Medicine & Health / Research

created Nov 24, 2008 | popularity 4.6 / 5 (5) | comments 0

The study was published in an online Early Edition issue of the Proceedings of the National Academy of Sciences, the week of November 24. Scripps Florida is a division of The Scripps Research Institute.