News tagged with notch pathway

Gatekeeper signal controls skin inflammation

A new study unravels key signals that regulate protective and sometimes pathological inflammation of the skin. The research, published online on January 26th in the journal Immunity by Cell Press, identifies a "gatekeeper" that, ...

Medicine & Health / Research

created Jan 26, 2012 | popularity not rated yet | comments 0

Previously unconnected molecular networks conspire to promote cancer

An inflammation-promoting protein triggers deactivation of a tumor-suppressor that usually blocks cancer formation via the NOTCH signaling pathway, a team of researchers led by scientists at The University of Texas MD Anderson ...

Medicine & Health / Cancer

created Dec 22, 2011 | popularity not rated yet | comments 0

Signaling pathway is 'executive software' of airway stem cells

Researchers at Duke University Medical Center have found out how mouse basal cells that line airways "decide" to become one of two types of cells that assist in airway-clearing duties. The findings could help provide new ...

Biology / Cell & Microbiology

created Jun 17, 2011 | popularity 3 / 5 (1) | comments 0 | with audio podcast

Study reveals origins of a cancer affecting the blood and bone marrow

A new study by the NYU Cancer Institute, an NCI-designated cancer center, sheds light on the origins of myeloid leukemia, a type of blood cancer that affects children and adults. The researchers discovered that novel mutations ...

Medicine & Health / Cancer

created May 12, 2011 | popularity not rated yet | comments 0 | with audio podcast

Buenos 'notch-es': Universal signaling pathway found to regulate sleep

Sleeping worms have much to teach people, a notion famously applied by the children's show "Sesame Street," in which Oscar the Grouch often reads bedtime stories to his pet worm Slimy. Based on research with their own worms, ...

Medicine & Health / Research

created May 05, 2011 | popularity not rated yet | comments 0 | with audio podcast

Fate in fly sensory organ precursor cells could explain human immune disorder

(June 21, 2009) - Notch signaling helps determine the fate of a number of different cell types in a variety of organisms, including humans. In an article that appears in the current issue of Nature Cell Biology, researchers at Bay ...

Biology / Cell & Microbiology

created Jun 21, 2009 | popularity 5 / 5 (1) | comments 0

Top notch decisions in the developing airways bring insights into lung disease

In the normal lung, the airways are lined by a balanced mixture of ciliated, secretory and neuroendocrine cells which perform functions as diverse as air humidification, detoxification, and clearance of environmental particles. ...

Medicine & Health / Research

created Jun 08, 2009 | popularity 5 / 5 (1) | comments 0