News tagged with notch pathway
Top notch decisions in the developing airways bring insights into lung disease
Jun 08, 2009 |
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In the normal lung, the airways are lined by a balanced mixture of ciliated, secretory and neuroendocrine cells which perform functions as diverse as air humidification, detoxification, and clearance of environmental particles. ...
New therapeutic target identified for rheumatoid arthritis
Nov 05, 2008 |
4.7 / 5 (3) |
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Researchers at Hospital for Special Surgery have identified a potential new therapeutic target that could be used to treat inflammatory disorders, such as rheumatoid arthritis.
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Critical protein helps mend damaged DNA
Dec 24, 2009 |
4.3 / 5 (4) |
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In order to preserve our DNA, cells have developed an intricate system for monitoring and repairing DNA damage. Yet precisely how the initial damage signal is converted into a repair response remains unclear. Researchers ...
Molecular anchor links the 2 inheritable diseases Fanconi anemia and Bloom's syndrome
Dec 24, 2009 |
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A new study establishes a molecular link that bridges two rare inherited disorders and explains why these diseases result in genetic instability. The research, published by Cell Press in the December 24th issue of the journal ...
Figitumumab has anti-tumor activity in Ewing's sarcoma
Dec 23, 2009 |
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A preliminary study of the anticancer drug figitumumab has found that it has antitumour activity in Ewing's sarcoma—a cancer which affects mainly teenage boys. The results have led to the drug's progression to a Phase 2 trial ...
A novel gene found for childhood-onset asthma
Dec 23, 2009 |
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Pediatric researchers have identified a novel gene involved in childhood asthma, in one of the largest gene studies to date of the common respiratory disease. Because the gene, called DENND1B, affects cells and signaling ...
Research yields new agent for some drug-resistant non-small cell lung cancers
Dec 23, 2009 |
5 / 5 (1) |
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The ability to make, test, and map the atomic structure of new anti-cancer agents has enabled a team of Dana-Farber Cancer Institute scientists to discover a compound capable of halting a common type of drug-resistant ...
Scientists discover how the brain encodes memories at a cellular level
Dec 23, 2009 |
4.9 / 5 (35) |
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Scientists at UC Santa Barbara have made a major discovery in how the brain encodes memories. The finding, published in the December 24 issue of the journal Neuron, could eventually lead to the development ...
Pollution linked to hospitalizations for pneumonia in older adults
Dec 23, 2009 |
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Older adults with long-term exposure to higher levels of pollution are at higher risk for hospitalization for pneumonia, according to researchers in Canada.
Accelerators and Light Sources of Tomorrow (Part 2: Accelerating with Light)
Dec 22, 2009 |
4.9 / 5 (7) |
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Accelerators are far from achieving the highest energies their builders aspire to, but size and cost may limit the kinds of facilities funding agencies can support. In the future, new kinds of machines will ...
Enzyme necessary for development of healthy immune system
Dec 22, 2009 |
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Mice without the deoxycytidine kinase (dCK) enzyme have defects in their adaptive immune system, producing very low levels of both T and B lymphocytes, the major players involved in immune response, according to a study by ...
EPA, Army Corps urged to consider separating Great Lakes, river basin
Dec 21, 2009 |
5 / 5 (2) |
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The once-radical idea of somehow plugging the Chicago Sanitary and Ship Canal to stop the flow of unwanted species from spilling between the Great Lakes and Mississippi River basin is quickly picking up political support.
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