News tagged with novel gene
Study identifies new gene associated with ALS
Feb 26, 2009 |
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A collaborative research effort spanning nearly a decade between researchers at Massachusetts General Hospital (MGH) and King’s College London (KCL) has identified a novel gene for inherited amyotrophic lateral sclerosis ...
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'Notch'ing up a role in the multisystem disease tuberous sclerosis complex
Dec 28, 2009 |
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Two independent teams of researchers have identified a role for enhanced activation of the signaling protein Notch in tumors characterized by inactivation of either the TSC1 or the TSC2 protein. As indicated by Warren Pear, ...
Newly Discovered Gene Mutation Linked to Nerve Diseases
Dec 28, 2009 |
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(PhysOrg.com) -- Researchers from the Northwestern University Feinberg School of Medicine have identified mutations in the gene for TRPV4 that cause two related degenerative motor nerve disorders, scapuloperoneal spinal muscular ...
Scientists discover a controller of brain circuitry
Medicine & Health / Neuroscience
Dec 28, 2009 |
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By combining a research technique that dates back 136 years with modern molecular genetics, a Johns Hopkins neuroscientist has been able to see how a mammal's brain shrewdly revisits and reuses the same molecular ...
Schizophrenia mouse model should improve understanding and treatment of the disorder
Dec 28, 2009 |
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Scientists have created what appears to be a schizophrenic mouse by reducing the inhibition of brain cells involved in complex reasoning and decisions about appropriate social behavior.
New RNA interference technique can silence up to five genes
Dec 28, 2009 |
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Researchers at MIT and Alnylam Pharmaceuticals report this week that they have successfully used RNA interference to turn off multiple genes in the livers of mice, an advance that could lead to new treatments ...
Genetic causes identified for disturbances in lipid metabolism
Dec 28, 2009 |
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Some of these common human gene variants are already known to be risk factors for diabetes mellitus. The pathomechanisms of diabetes have intrigued physicians and been the subject of much debate for many decades. These new ...
One step closer to closure: Neuroscientists discovery key to spinal cord defects
Medicine & Health / Neuroscience
Dec 28, 2009 |
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Spinal cord disorders like spina bifida arise during early development when future spinal cord cells growing in a flat layer fail to roll up into a tube. In the Dec. 6 issue of Nature Cell Biology, researchers from the Jo ...
Scientists identify protein that keeps stem cells poised for action
Dec 24, 2009 |
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(PhysOrg.com) -- Like a child awaiting the arrival of Christmas, embryonic stem cells exist in a state of permanent anticipation. They must balance the ability to quickly become more specialized cell types with the cellular ...
Molecular anchor links the 2 inheritable diseases Fanconi anemia and Bloom's syndrome
Dec 24, 2009 |
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A new study establishes a molecular link that bridges two rare inherited disorders and explains why these diseases result in genetic instability. The research, published by Cell Press in the December 24th issue of the journal ...
'Self-seeding' of cancer cells may play a critical role in tumor progression
Dec 24, 2009 |
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Cancer progression is commonly thought of as a process involving the growth of a primary tumor followed by metastasis, in which cancer cells leave the primary tumor and spread to distant organs. A new study by researchers ...
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