News tagged with nuclear genes
Discovery of extremely long-lived proteins may provide insight into cell aging
One of the big mysteries in biology is why cells age. Now scientists at the Salk Institute for Biological Studies report that they have discovered a weakness in a component of brain cells that may explain ...
Feb 03, 2012 |
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PET technique promises better detection and response assessment for Non-Hodgkin's lymphoma
Positron emission tomography (PET) and a molecular imaging agent that captures the proliferation of cancer cells could prove to be a valuable method for imaging a form of Non-Hodgkin's disease called mantle cell lymphoma, ...
Dec 21, 2011 |
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High-energy lifestyles led to evolution of the sexes
Scientists are a step closer to explaining one of the most enduring mysteries of modern biology; why are there males and females?
Dec 19, 2011 |
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Nuclear receptors battle it out during metamorphosis in new fruit fly model
Growing up just got more complicated. Thomas Jefferson University biochemistry researchers have shown for the first time that the receptor for a major insect molting hormone doesn't activate and repress genes ...
Oct 06, 2011 |
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Manipulated gatekeeper: How viruses find their way into the cell nucleus
Adenoviruses cause respiratory diseases and are more dangerous for humans than previously assumed. They manipulate gatekeeper molecules and infiltrate the cell nucleus with the aid of the host cell. A team of researchers ...
Oct 03, 2011 |
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Scientists describe mechanism for rare muscle disease
(Medical Xpress) -- A team of scientists from the Friedrich Miescher Institute for Biomedical Research and the Hebrew University of Jerusalem describe in C. elegans the process leading to a rare form of Emery-Dreifuss ...
Oct 03, 2011 |
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In next-gen DNA sequence, new answers to a rare and devastating disease
In Leigh syndrome, infants are born apparently healthy only to develop movement and breathing disorders that worsen over time, often leading to death by the age of 3. The problem is that the mitochondria responsible for powering ...
Sep 06, 2011 |
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PGD can permit the birth of healthy children to women carrying mitochondrial DNA disease
Pre-implantation genetic diagnosis (PGD) can give women at risk of passing on a mitochondrial DNA disorder to their offspring a good chance of being able to give birth to an unaffected child, a researcher told the annual ...
May 30, 2011 |
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Mothers curse linked to male infertility
(Medical Xpress) -- Researchers have discovered the first real evidence of the 'mother's curse' and its connection to male infertility due to genetic mutations in mitochondria. Led by Dr. Damian Dowling from Monash University ...
Scientists create new genetic model of premature aging diseases
Working with a group of national and international researchers, scientists from the Florida campus of The Scripps Research Institute have developed a new genetic model of premature aging disorders that could shed light on ...
Apr 29, 2011 |
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Keeping retinoic acid in check
Neurobiologists from the Friedrich Miescher Institute for Biomedical Research (FMI) of the Novartis Research Foundation are the first to describe a mechanism that controls the synthesis of retinoic acid in ...
Apr 19, 2011 |
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Not all clones the same
Despite their name, not all clones are created equal. This is especially true for the products of somatic cell nuclear transfer (SCNT), which entails the transplantation of the nucleus from a mature somatic ...
Nov 05, 2010 |
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Nuclear pore complexes harbor new class of gene regulators
Nuclear pore complexes are best known as the communication channels that regulate the passage of all molecules to and from a cell's nucleus. Researchers at the Salk Institute for Biological Studies, however, ...
Feb 04, 2010 |
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New concoction reprograms differentiated cells into pluripotent stem cells
In the new issue of the journal Cell Stem Cell, Singapore scientists report the surprising discovery that a novel transcription factor, Nr5a2, can replace one of the classical reprogramming factors, Oct 4, to significantly increa ...
Jan 21, 2010 |
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Study shows gene positions may aid cancer diagnosis
Certain genes switch their nuclear position in tumor cells, offering a potential new method of diagnosing cancer, say researchers from the National Cancer Institute. The study by Meaburn et al. will be published ...
Dec 07, 2009 |
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