News tagged with obese mice
Is obesity a ciliopathy, triggered by malfunctioning primary cilia?
Is obesity a ciliopathy, a disorder such as polycystic kidney disease (PKD), which is triggered by a defect in the microscopic hair-like cilia that protrude from virtually every cell of humans and other vertebrates?
Dec 06, 2011 |
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Super athletic mice are fit because their muscles burn more sugar
Muscle performance and fitness are partly determined by how well your muscle cells use sugar as a fuel source. In turn, exercising improves the muscle's ability to take up sugars from the bloodstream and burn ...
Nov 30, 2011 |
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Enzyme boosts metabolism, prevents weight gain in mice
In a new study, scientists report that they substantially curbed weight gain, improved metabolism, and improved the efficacy of insulin in mice by engineering them to express a specific human enzyme in their fat tissue. Although ...
Nov 14, 2011 |
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Study shows estrogen works in the brain to keep weight in check
A recent UT Southwestern Medical Center study found that estrogen regulates energy expenditure, appetite and body weight, while insufficient estrogen receptors in specific parts of the brain may lead to obesity.
Oct 20, 2011 |
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Green tea helps mice keep off extra pounds
Green tea may slow down weight gain and serve as another tool in the fight against obesity, according to Penn State food scientists.
Oct 04, 2011 |
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Diabetes and cancer: A shared biological basis
Contrary to what you might think, cancer and diabetes appear to have some biology in common. According to a report in the September 30th issue of the Cell Press journal, Cell, a pathway that initially drew attention for it ...
Sep 29, 2011 |
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Exercise eases arthritis in obese mice even without weight loss
Adding another incentive to exercise, scientists at Duke University Medical Center have found that physical activity improves arthritis symptoms even among obese mice that continue to chow down on a high-fat diet.
Sep 27, 2011 |
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Researchers identify pathways leading to activation of good fat
Researchers at the Joslin Diabetes Center have identified for the first time two molecular pathways that are critical to activating a type of "good" fat found in the body, a discovery that could play an important ...
Sep 21, 2011 |
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High-fat diet and lack of enzyme can lead to heart disease in mice
It's no secret that a high-fat diet isn't healthy. Now researchers have discovered a molecular clue as to precisely why that is.
Sep 12, 2011 |
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Compound improves health, increases lifespan of obese mice
(Medical Xpress) -- Researchers have reported that obese male mice treated with a synthetic compound called SRT1720 were healthier and lived longer compared to non-treated obese mice. The experimental compound was found to ...
Aug 22, 2011 |
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Findings in mice have potential to curb obesity, Type 2 diabetes
Scientists at the National Institutes of Health have uncovered a pathway in mice that allows white fat – a contributor to obesity and type 2 diabetes – to burn calories in a way that's normally found in brown fat ...
Jul 05, 2011 |
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Obese dieters' brain chemistry works against their weight-loss efforts
If you've been trying to lose weight and suspect your body's working against you, you may be right, according to a University of Illinois study published in Obesity.
Jun 23, 2011 |
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Anti-obesity vaccine reduces food consumption in animals
A new therapeutic vaccine to treat obesity by suppressing the appetite-stimulating hormone ghrelin decreases food intake and increases calorie burning in mice, a new study finds. The results will be presented Sunday at The ...
Jun 06, 2011 |
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The couch potato effect: Deletion of key muscle protein inhibits exercise
Daniel Kelly, M.D., and his colleagues at Sanford-Burnham Medical Research Institute (Sanford-Burnham) at Lake Nona have unveiled a surprising new model for studying muscle function: the couch potato mouse. While these mice ...
Nov 30, 2010 |
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Overactive FTO gene does cause overeating and obesity
(PhysOrg.com) -- Scientists have gained strong confirmation of the direct connection between the FTO gene and obesity, obtaining the first direct evidence that overactivity of the gene leads to overeating ...
Nov 15, 2010 |
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