News tagged with osteoblasts

Osteoblast

Osteoblasts (from the Greek words for "bone" and "germ" or embryonic) are mononucleate cells that are responsible for bone formation; in essence, osteoblasts are specialized fibroblasts that in addition to fibroblastic products, express bone sialoprotein and osteocalcin.

Osteoblasts produce a matrix of osteoid, which is composed mainly of Type I collagen. Osteoblasts are also responsible for mineralization of this matrix. Zinc, copper and sodium are some of the minerals required in this process. Bone is a dynamic tissue that is constantly being reshaped by osteoblasts, in charge of production of matrix and mineral, and osteoclasts, which remodel the tissue. Osteoblast cells tend to decrease with age, affecting the balance of formation and resorption in the bone tissue.

For more information about Osteoblast, read the full article at Wikipedia.
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Pituitary hormone TSH found to directly influence bone growth

Researchers at Mount Sinai School of Medicine have found that thyroid-stimulating hormone (TSH), a hormone produced in the anterior pituitary gland that regulates endocrine function in the thyroid gland, can promote bone ...

Medicine & Health / Research

created Sep 13, 2011 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Osteoblasts are bone idle without Frizzled-9

New research shows that the Wnt receptor Frizzled-9 (Fzd9) promotes bone formation, providing a potential new target for the treatment of osteoporosis. The study appears online on March 14 in The Journal of ...

Biology / Cell & Microbiology

created Mar 14, 2011 | popularity not rated yet | comments 0

Salmon in hot water

Rearing juvenile salmon at the relatively high temperature of 16 C causes skeletal deformities in the fish. Researchers writing in the open access journal BMC Physiology investigated both the magnitude and mechanisms of thi ...

Biology / Ecology

created Jul 05, 2010 | popularity not rated yet | comments 0

Blood tells old cells to act young

(PhysOrg.com) -- Harvard Stem Cell Institute (HSCI) researchers at the Joslin Diabetes Center (JDC) have taken a major step toward eventually understanding -- and perhaps slowing -- the aging process.

Medicine & Health / Research

created Jan 27, 2010 | popularity 4.9 / 5 (12) | comments 4 | with audio podcast

Experimental Approach May Reverse Rheumatoid Arthritis and Osteoporosis

(PhysOrg.com) -- Researchers have identified a mechanism that may keep a well known signaling molecule from eroding bone and inflaming joints, according to an early study published online today in the Journal of Clinical In ...

Medicine & Health / Research

created Sep 21, 2009 | popularity 4.8 / 5 (13) | comments 0

Researchers identify protein involved in causing gum disease, osteoporosis, arthritis

Investigators at Hospital for Special Surgery, collaborating with researchers from other institutions, have contributed to the discovery that a gene called interferon regulator factor-8 (IRF-8) is involved in the development ...

Medicine & Health / Research

created Aug 30, 2009 | popularity 4.7 / 5 (3) | comments 0

Stem cells could halt osteoporosis, promote bone growth

While interferon gamma sounds like an outer space weapon, it's actually a hormone produced by our own bodies, and it holds great promise to repair bones affected by osteoporosis. In a new study published in the journal Stem Ce ...

Medicine & Health / Research

created Mar 04, 2009 | popularity not rated yet | comments 0

Cell injections accelerate fracture healing

Long bone fractures heal faster after injections of bone-building cells. Research published in the open access journal BMC Musculoskeletal Disorders has shown that osteoblast cells cultured from a patient's own bone marrow ...

Medicine & Health / Diseases

created Feb 12, 2009 | popularity 4.5 / 5 (2) | comments 0