News tagged with p53 function
Explaining heart failure as a cause of diabetes
Either heart failure or diabetes alone is bad enough, but oftentimes the two conditions seem to go together. Now, researchers reporting in the January Cell Metabolism appear to have found the culprit that leads from heart ...
Jan 03, 2012 |
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The 2 faces of Mdmx: Why some tumors don't respond to radiation and chemotherapy
A tightly controlled system of checks and balances ensures that a powerful tumor suppressor called p53 keeps a tight lid on unchecked cell growth but doesn't wreak havoc in healthy cells. In their latest study, ...
Jul 06, 2009 |
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Search results for p53 function
Why cholesterol-lowering statins might treat cancer
Cholesterol-lowering statins seem to keep breast cancer at bay in some patients. Now researchers reporting in the January 20th issue of the journal Cell, a Cell Press publication, provide clues about how statins might yield ...
Jan 19, 2012 |
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First analysis of tumor-suppressor interactions with whole genome in normal human cells
Scientists investigating the interactions, or binding patterns, of a major tumor-suppressor protein known as p53 with the entire genome in normal human cells have turned up key differences from those observed in cancer cells. ...
Nov 30, 2011 |
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Study probes potential link between cancer and a common chemical in consumer products
A study led by a group of Nanyang Technological University (NTU) researchers has found that a chemical commonly used in consumer products can potentially cause cancer.
Nanotechnology / Bio & Medicine
Nov 29, 2011 |
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Scientists develop new class of small molecules through innovative chemistry
Inspired by natural products, scientists on the Florida campus of the Scripps Research Institute have created a new class of small molecules with the potential to serve as a rich foundation for drug discovery.
Nov 20, 2011 |
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Molecular link between diabetes and cancer described
Developing type 2 diabetes is a lengthy process. An early sign that it has begun is high levels of insulin in the blood. As long as the insulin-producing beta cells are able to compensate for the increased demand, for example ...
Nov 15, 2011 |
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Scientists discover nucleoli damage could kill cancer cells
(Medical Xpress) -- Damaging a cell’s nucleolus could destroy cancer cells by increasing levels of the most important tumour prevention protein, p53, reveals research presented at the National Cancer Research Institute ...
Nov 08, 2011 |
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New anti-inflammatory drugs might help avoid side effects of steroids
A new class of anti-inflammatory drugs may one day serve as an alternative to steroid medications and possibly help avoid the serious side effects of steroids, based on research findings at the Salk Institute for Biological ...
Oct 25, 2011 |
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Researchers map genome of advanced, lethal prostate cancers and discover 'hypermutation'
A team of researchers at Fred Hutchinson Cancer Research Center and the University of Washington has conducted the first comprehensive assessment of every gene in the genome of advanced, lethal prostate cancer. Until now, ...
Sep 26, 2011 |
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A chaperone for the 'guardian of the genome'
The protein p53 plays an essential role in the prevention of cancer by initiating the controlled death of a cell with damaged genes which is in danger to transform into a cancerous cell. The heat shock protein Hsp90, in turn, ...
Sep 07, 2011 |
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Study shows relationship between two mutated genes can dictate outcome of prostate cancer
Of the 250,000 American men who will be diagnosed with prostate cancer this year, very few of them—about 1 percent—will develop lethal, metastatic disease. Finding a way to distinguish between this small cohort ...
Aug 15, 2011 |
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List of search results for p53 function
