News tagged with p53 genes
Fat droplet nanoparticle delivers tumor suppressor gene to tumor and metastatic cells
Nanotechnology / Bio & Medicine
Apr 20, 2009 |
5 / 5 (3) |
0
Dr. Esther Chang describes the most recent developments in human trials of the first systemic, non-viral, tumor-targeted, nanoparticle method designed to restore normal gene function to tumor cells while completely bypassing ...
Regulatory molecule for tumor formation or suppression identified
Mar 17, 2009 |
not rated yet |
0
One of the small regulatory molecules, named microRNA-125b, is a novel regulator of p53, an important protein that safeguards cells against cancers, Singapore and U.S. scientists report in the March 17, 2009 issue of the ...
Search results for p53 genes
Newly discovered gene plays vital role in cancer
Feb 27, 2009 |
4.8 / 5 (8) |
0
(PhysOrg.com) -- Gene p53 protects against cancer and is usually described as the most important gene in cancer research. However, scientists at the Swedish medical university Karolinska Institutet have now shown that a previously ...
Effect of mutant p53 stability on tumorigenesis and drug design
May 15, 2008 |
4.5 / 5 (2) |
0
In the May 15th issue of G&D, Dr. Guillermina Lozano (MD Anderson Cancer Center) and colleagues reveal how the stabilization of a mutated form of p53 affects oncogenesis, and lends startling new insight into the potential ...
MicroRNA undermines tumor suppression
Mar 17, 2009 |
not rated yet |
0
A small piece of RNA, or microRNA (miRNA), ratchets down the activity of the tumor-suppressor gene p53, according to a study by Whitehead Institute and National University of Singapore researchers.
Stabilizing cancer-fighting p53 can also shield a metastasis-promoter
May 22, 2008 |
4 / 5 (2) |
1
Efforts to protect the tumor-suppressor p53 could just as easily shelter a mutant version of the protein, causing cancer cells to thrive and spread rather than die, according to research by scientists at The University of ...
Research shows cell's inactive state is critical for effectiveness of cancer treatment
Biology /
Jan 09, 2009 |
5 / 5 (1) |
0
A new study sheds light on a little understood biological process called quiescence, which enables blood-forming stem cells to exist in a dormant or inactive state in which they are not growing or dividing. According to the ...
Tumor mutations can predict chemo success
Aug 06, 2009 |
not rated yet |
2
(PhysOrg.com) -- New work by MIT cancer biologists shows that the interplay between two key genes that are often defective in tumors determines how cancer cells respond to chemotherapy.
Singapore scientists discover widely sought molecular key to understanding p53 tumor suppressor gene
Oct 13, 2009 |
not rated yet |
0
Scientists at the Singapore Immunology Network (SIgN) have determined how the master gene regulator p53 could switch a gene in a cell "on" or "off" by recognizing specific sequences of nucleotides in the gene's DNA.
Novel model of osteosarcoma
Jun 15, 2008 |
3.5 / 5 (2) |
0
In the June 15th issue of G&D, Dr. Stuart Orkin (HHMI, Dana-Farber Cancer Institute, Children's Hospital Boston) and colleagues present a new mouse model of osteosarcoma.
Researchers discover how tumor suppressor inhibits cell growth
Aug 07, 2008 |
4 / 5 (1) |
0
Genes that inhibit the spontaneous development of cancer are called tumor suppressor genes. One of the major tumor suppressors is p53, a protein that acts in the cell nucleus to control the expression of other genes whose ...
Common cancer gene sends death order to tiny killer
May 31, 2007 |
4.5 / 5 (6) |
0
Scientists at Johns Hopkins have discovered one way the p53 gene does what it's known for—stopping the colon cancer cells. Their report will be published in the June 8 issue of Molecular Cell.
List of search results for p53 genes
