News tagged with p53 protein
Researchers pinpoint a new enemy for tumor-suppressor p53
Jun 26, 2009 |
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Researchers at The University of Texas M. D. Anderson Cancer Center have identified a protein that marks the tumor suppressor p53 for destruction, providing a potential new avenue for restoring p53 in cancer ...
Most common brain cancer may originate in neural stem cells
Jun 01, 2009 |
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University of Michigan scientists have found that a deficiency in a key tumor suppressor gene in the brain leads to the most common type of adult brain cancer. The study, conducted in mice that mimic human cancer, points ...
New research on the 'guardian of the genome'
May 12, 2009 |
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(PhysOrg.com) -- Protein p53 protects the body against cancer and is knocked out in many cancer tumours. Researchers at Karolinska Institutet have identified two molecules that can restore p53's cancer-killing properties. ...
Chemopreventive isothiocyanates selectively depletes mutant p53 in tumor cells
Apr 20, 2009 |
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Researchers at Lombardi Comprehensive Cancer Center at Georgetown University Medical Center have demonstrated that naturally-occurring compounds can selectively deplete mutant p53 and restore "wild type" function to p53 in ...
Search results for p53 protein
Stabilizing cancer-fighting p53 can also shield a metastasis-promoter
May 22, 2008 |
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Efforts to protect the tumor-suppressor p53 could just as easily shelter a mutant version of the protein, causing cancer cells to thrive and spread rather than die, according to research by scientists at The University of ...
Newly discovered gene plays vital role in cancer
Feb 27, 2009 |
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(PhysOrg.com) -- Gene p53 protects against cancer and is usually described as the most important gene in cancer research. However, scientists at the Swedish medical university Karolinska Institutet have now shown that a previously ...
Protein can help cells or cause cancer, researcher finds
Jul 07, 2009 |
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A Purdue University scientist has discovered a key process in cell growth that can lead to the formation of tumors.
MicroRNA undermines tumor suppression
Mar 17, 2009 |
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A small piece of RNA, or microRNA (miRNA), ratchets down the activity of the tumor-suppressor gene p53, according to a study by Whitehead Institute and National University of Singapore researchers.
Research shows cell's inactive state is critical for effectiveness of cancer treatment
Biology /
Jan 09, 2009 |
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A new study sheds light on a little understood biological process called quiescence, which enables blood-forming stem cells to exist in a dormant or inactive state in which they are not growing or dividing. According to the ...
Estrogen can reduce stroke damage by inactivating protein
Jul 16, 2009 |
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Estrogen can halt stroke damage by inactivating a tumor-suppressing protein known to prevent many cancers, Medical College of Georgia researchers say.
Study pinpoints protein's role in cancer spread
Jul 24, 2006 |
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Edinburgh scientists have identified the way a specific cell protein can trigger the spread of cancer. The study by researchers in the Cell Signalling Unit, University of Edinburgh Cancer Research Centre could pave the way ...
Antitumor activity of nutlin-3 in neuroblastoma with wild-type p53
Nov 10, 2009 |
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The small-molecule inhibitor nutlin-3 may be a viable treatment option for neuroblastoma patients with wild-type p53 activity, according to a new study published online November 10 in the Journal of the National Cancer In ...
Study details regulation of vital tumor suppressor gene p53
Sep 05, 2007 |
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So vital is the p53 tumor suppressor gene in controlling cancer that its dysfunction is linked to more than half of human cancers. At the same time, the gene’s capacity for shutting down cell growth, even causing cells to ...
How eating fruit and vegetables can improve cancer patients' response to chemotherapy
Oct 22, 2008 |
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The leading cause of death in all cancer patients continues to be the resistance of tumor cells to chemotherapy, a form of treatment in which chemicals are used to kill cells.
List of search results for p53 protein
