News tagged with p53 tumor suppressor gene
Toward new drugs that turn genes on and off
Jun 04, 2009 |
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Scientists in Michigan and California are reporting an advance toward development of a new generation of drugs that treat disease by orchestrating how genes in the body produce proteins involved in arthritis, ...
Fat droplet nanoparticle delivers tumor suppressor gene to tumor and metastatic cells
Nanotechnology / Bio & Medicine
Apr 20, 2009 |
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Dr. Esther Chang describes the most recent developments in human trials of the first systemic, non-viral, tumor-targeted, nanoparticle method designed to restore normal gene function to tumor cells while completely bypassing ...
Search results for p53 tumor suppressor gene
New suppressor of common liver cancer
Dec 15, 2009 |
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Tumor suppressor genes make proteins that help control cell growth. Mutations in these genes that generate nonfunctional proteins can contribute to tumor development and progression. One of the most well-known tumor suppressor ...
Scientists identify natural anti-cancer defenses
Dec 11, 2009 |
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Canadian researchers have discovered a novel molecular mechanism that prevents cancer. In the December 11 edition of the prestigious journal Molecular Cell, scientists from the Université de Montréal and th ...
New understanding of how to prevent destruction of a tumor suppressor
Dec 07, 2009 |
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Researchers from the Indiana University School of Medicine and colleagues at the University of Texas Southwestern and Case Western University have determined how the protein Mdm2, which is elevated in late-stage ...
Researchers prove key cancer theory
Dec 07, 2009 |
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Mayo Clinic researchers have proven the longstanding theory that changes in the number of whole chromosomes -- called aneuploidy -- can cause cancer by eliminating tumor suppressor genes. Their findings, which appear in the ...
Tiny RNA has big impact on lung cancer tumors
Dec 07, 2009 |
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Researchers from Yale University and Mirna Therapeutics, Inc., reversed the growth of lung tumors in mice using a naturally occurring tumor suppressor microRNA. The study reveals that a tiny bit of RNA may one day play a ...
Human Mdm2: A new molecular link to late-stage metastatic breast cancer
Dec 02, 2009 |
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A large proportion of late-stage breast cancers that have spread to other parts of the body (metastatic breast cancers) are characterized by overexpression of the protein Mdm2.
Cancer metabolism discovery uncovers new role of IDH1 gene mutation in brain cancer
Nov 22, 2009 |
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Agios Pharmaceuticals today announced that its scientists have established, for the first time, that the mutated IDH1 gene has a novel enzyme activity consistent with a cancer-causing gene, or oncogene. This breakthrough ...
New combination therapy could deliver powerful punch to breast cancer
Nov 16, 2009 |
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A powerful new breast cancer treatment could result from packaging one of the newer drugs that inhibits cancer's hallmark wild growth with another that blocks a primordial survival technique in which the cancer ...
How cells tolerate DNA damage -- start signal for cell survival program identified
Nov 16, 2009 |
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Cancer researchers of the Max Delbrück Center for Molecular Medicine (MDC) Berlin-Buch, Germany, have gained new insights into how cells react to DNA damage. Dr. Michael Stilmann, Dr. Michael Hinz and Professor Claus Scheidereit ...
Discovery in worms points to more targeted cancer treatment
Nov 10, 2009 |
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Researchers at Queen's University have found a link between two genes involved in cancer formation in humans, by examining the genes in worms. The groundbreaking discovery provides a foundation for how tumor-forming ...
List of search results for p53 tumor suppressor gene
