Related topics: type 1 diabetes · diabetes · beta cells

Scientists identify first negative regulator of NOX4 translation

Nicotinamide adenine dinucleotide phosphate oxidase 4 (NADPH oxidase 4, NOX4) is an important member of the NADPH oxidase family that is primarily responsible for the production of H2O2. The regulation of NOX4 activity is ...

Diabetes in mice cured rapidly using human stem cell strategy

Researchers have converted human stem cells into insulin-producing cells and demonstrated in mice infused with such cells that blood sugar levels can be controlled and diabetes functionally cured for nine months.

Breakthrough in understanding how stem cells become specialized

Scientists at Sanford Burnham Prebys Medical Discovery Institute (SBP) have made a major advance in understanding how the cells of an organism, which all contain the same genetic information, come to be so diverse. A study ...

Protons power protein portal to push zinc out of cells

Researchers at The Johns Hopkins University report they have deciphered the inner workings of a protein called YiiP that prevents the lethal buildup of zinc inside bacteria. They say understanding YiiP's movements will help ...

Human stem cells converted to functional lung cells

For the first time, scientists have succeeded in transforming human stem cells into functional lung and airway cells. The advance, reported by Columbia University Medical Center (CUMC) researchers, has significant potential ...

page 1 from 2