Related topics: genes

Scientists zero in on endgame for nasty bacteria

Medications were once discovered by finding active ingredients in traditional remedies or by serendipitous discovery. A relatively new approach is to understand how disease and infection are controlled at the molecular level, ...

Team studies mechanism of H. influenzae biofilm formation

A research study identifying novel bacterial physiology in the creation of biofilms by Nationwide Children's Hospital scientists has been published in the current issue of Proceedings of the National Academy of Sciences (PNAS).

The evolutionary secret of H. pylori to survive in the stomach

Professor Frédéric Veyrier's most recent research, in collaboration with the team of Professor Hilde De Reuse at the Institut Pasteur, has shed light on key genes essential to the pathogenesis of Helicobacter pylori bacterium, ...

Recent research uncovers surprises about antibiotic resistance

It's thought that antibiotic resistance is associated with a fitness cost, meaning that bacteria that develop antibiotic resistance must sacrifice something in order to do so. Because of this, proper use of antibiotics should ...

Bacterial brawls mark life in the gut's microbiome

Bacterially speaking, it gets very crowded in the human gut, with trillions of cells jostling for a position to carry out a host of specialized and often crucial tasks. A new Yale study, published the week of March 7 in the ...

New fish test for virus is nonlethal

(Phys.org) —Cornell researchers have successfully identified the presence of a deadly virus—the viral hemorrhagic septicemia virus (VHSV)—by using techniques that are not lethal to fish.

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Pathogenesis

The pathogenesis of a disease is the mechanism by which the disease is caused. The term can also be used to describe the origin and development of the disease and whether it is acute, chronic or recurrent. The word comes from the Greek pathos, "disease", and genesis, "creation".

Types of pathogenesis include microbial infection, inflammation, malignancy and tissue breakdown.

Most diseases are caused by multiple pathogenetical processes together. For example, certain cancers arise from dysfunction of the immune system (skin tumors and lymphoma after a renal transplant, which requires immunosuppression).

Often, a potential etiology is identified by epidemiological observations before a pathological link can be drawn between the cause and the disease.

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