News tagged with pathogenic mitochondrial
Large reservoir of mitochondrial DNA mutations identified in humans
Aug 11, 2008 |
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Researchers at the University of Newcastle, England, and the Virginia Bioinformatics Institute at Virginia Tech in the United States have revealed a large reservoir of mitochondrial DNA mutations present in the general population. ...
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New clues about mitochondrial 'growth spurts'
Mar 02, 2009 |
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Mitochondria are restless, continually merging and splitting. But contrary to conventional wisdom, the size of these organelles depends on more than fusion and fission, as Berman et al. show. Mitochondrial ...
Quick and easy diagnosis for mitochondrial disorders
Oct 22, 2009 |
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Soon you could be genetically screened for mitochondrial disorders quickly and comprehensively. Research published in BioMed Central's open access journal, Genome Medicine, outlines an innovative clinical diagnostic test f ...
Mitochondria defects linked to social behavior and spatial memory
Dec 04, 2007 |
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Respiration deficiencies in mitochondria, the cell’s powerhouses, are associated with changed social behavior and spatial memory in laboratory mice, report scientists at the American Society for Cell Biology 47th Annual Meeting. ...
Disease-causing Escherichia coli: 'I will survive'
Sep 09, 2009 |
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Strains of Escherichia coli bacteria that cause food poisoning have been shown to have marked differences in the numbers of genes they carry compared to laboratory strains of E. coli. Some of these genes may enable them t ...
Neurological disorder in golden retriever dogs caused by a mutation in mitochondrial DNA
May 29, 2009 |
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Sensory ataxic neuropathy (SAN) is a recently identified neurological disorder in Golden Retriever dogs with onset during puppyhood. Affected dogs move in an uncoordinated manner and have sensory deficits. Researchers from ...
Key protein in cellular respiration discovered
Apr 08, 2009 |
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Many diseases derive from problems with cellular respiration, the process through which cells extract energy from nutrients. Researchers at the Swedish medical university Karolinska Institutet have now discovered a new function ...
Alzheimer's disease linked to mitochondrial damage
Apr 02, 2009 |
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Investigators at Burnham Institute for Medical Research (Burnham) have demonstrated that attacks on the mitochondrial protein Drp1 by the free radical nitric oxide—which causes a chemical reaction called S-nitrosylation—mediates ...
'Anti-Atkins' low protein diet extends lifespan in flies
Oct 01, 2009 |
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Flies fed an "anti-Atkins" low protein diet live longer because their mitochondria function better. The research, done at the Buck Institute for Age Research, shows that the molecular mechanisms responsible for the lifespan ...
How mitochondrial gene defects impair respiration, other major life functions
Sep 24, 2009 |
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Researchers are delving into abnormal gene function in mitochondria, structures within cells that power our lives. Mitochondria are the place where energy is generated from the most basic molecules of food. Because this function ...
Bad mitochondria may actually be good for you
Jul 22, 2009 |
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Mice with a defective mitochondrial protein called MCLK1 produce elevated amounts of reactive oxygen when young; that should spell disaster, yet according to a study in this week's JBC these mice actually age at a slower ...
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