Enzyme 'atlas' helps researchers decipher cellular pathways

One of the most important classes of human enzymes are protein kinases—signaling molecules that regulate nearly all cellular activities, including growth, cell division, and metabolism. Dysfunction in these cellular pathways ...

Fungus produces active agent in a medicinal herb

Tatarinow's aster is used in traditional Chinese medicine to treat a number of ailments; the plant contains an active ingredient known as astin—and it is this agent which cancer researchers are now investigating. However, ...

Fully identified—the pathway of protons

In their catalytic center, hydrogenases manufacture molecular hydrogen (H2) from two protons and two electrons. They extract the protons required for this process from the surrounding water and transfer them – via a transport ...

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