News tagged with pathway
Antitumor activity of nutlin-3 in neuroblastoma with wild-type p53
15 hours ago |
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The small-molecule inhibitor nutlin-3 may be a viable treatment option for neuroblastoma patients with wild-type p53 activity, according to a new study published online November 10 in the Journal of the National Cancer In ...
Researchers to develop novel drug detection technology using software that acts like a robotic scientist
Chemistry / Analytical Chemistry
Nov 09, 2009 |
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(PhysOrg.com) -- Every time a person snorts cocaine, it doesn’t just go to his or her head: It also provokes a response in the immune system, creating special biomolecules that may serve as a permanent record of each exposure.
Tapeworm Drug May Hold Promise For Colon Cancer, Future Research
Nov 04, 2009 |
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(PhysOrg.com) -- Duke University Medical Center researchers have discovered an already-FDA-approved compound that can effectively “silence” a cell receptor shown to interfere with chemotherapy.
Two-In-One Punch Knocks Out Drug Resistant Cancer Cells
Nanotechnology / Bio & Medicine
Nov 04, 2009 |
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(PhysOrg.com) -- Cancer cells, like bacteria, can develop resistance to drug therapy, leading to relapse of disease. One approach showing promise in overcoming multidrug resistance in tumors is to combine two different anticancer ...
Researcher studies blood vessels that feed tumors
Nov 03, 2009 |
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(PhysOrg.com) -- Federal stimulus funding helps Cornell researchers create tiny 3-D models of tumors to mimic conditions necessary for the development of vascular systems by tumors.
Stress-induced changes in brain circuitry linked to cocaine relapse
Oct 30, 2009 |
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(PhysOrg.com) -- Stress-evoked changes in circuits that regulate serotonin in certain brain regions can precipitate a low mood and a relapse in cocaine-seeking.
JAX publishes online tool for exploring autoimmune disease gene networks
Oct 29, 2009 |
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Currently, 5-8% of the U.S. population is afflicted with an autoimmune disease. Many of these are chronic and require life-long care. Moreover, different autoimmune diseases aggregate within a single family, ...
Researchers use drug-radiation combo to eradicate lung cancer
Oct 29, 2009 |
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Researchers at UT Southwestern Medical Center have eliminated non-small cell lung (NSCL) cancer in mice by using an investigative drug called BEZ235 in combination with low-dose radiation.
Research could boost coastal economics with crustacean molting on demand (w/ Video)
Oct 27, 2009 |
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University of Alabama at Birmingham researchers are close to unraveling intricate cellular pathways that control molting in blue crabs. The discoveries could revolutionize the soft-shell crab industry, generating ...
Genes that drive you to drink (but don't make you an alcoholic)
Oct 26, 2009 |
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Your genetic make up may predispose you to drink more but may not increase your genetic risk for alcoholism (alcohol dependence). Research published in the open access journal, BMC Biology, pinpoints genetic pathways and ge ...
Researchers reverse pulmonary arterial hypertension in mouse models
Oct 25, 2009 |
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Researchers at the University of California, San Diego, have identified a key protein that promotes the development of pulmonary arterial hypertension in humans and mice. This groundbreaking discovery has implications for ...
Alcohol tolerance 'switch' found
Oct 21, 2009 |
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Researchers at North Carolina State University have found a genetic "switch" in fruit flies that plays an important role in making flies more tolerant to alcohol.
Protein interaction network can respond Helicobacter pylori infection?
Oct 16, 2009 |
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Helicobacter pylori (H pylori) is a gram negative bacterium which infects about 50% of the world population. H pylori colonization causes a strong systemic immune response. Various tools have been employed to identify the rela ...
Singapore scientists discover widely sought molecular key to understanding p53 tumor suppressor gene
Oct 13, 2009 |
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Scientists at the Singapore Immunology Network (SIgN) have determined how the master gene regulator p53 could switch a gene in a cell "on" or "off" by recognizing specific sequences of nucleotides in the gene's DNA.
Too much of a good thing? Scientists explain cellular effects of vitamin A overdose and deficiency
Oct 08, 2009 |
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If a little vitamin A is good, more must be better, right? Wrong! New research published online in the FASEB Journal shows that vitamin A plays a crucial role in energy production within cells, explaining why too much or too ...
