News tagged with pathway
Crosstalk between critical cell-signaling pathways holds clues to tumor invasion and metastasis
8 hours ago |
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Two signaling pathways essential to normal human development - the Wnt/Wingless (Wnt) and epidermal growth factor receptor (EGFR) pathways - interact in ways that can promote tumor cell invasion and metastasis, researchers ...
Researchers identify proteins in lung cancer cells that may provide potential drug targets
15 hours ago |
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Researchers from Boston University School of Medicine (BUSM) and the Boston University Biomedical Engineering Department have identified a number of proteins whose activation allows them to distinguish between cancer and ...
Systems biology approach provides insulin resistance insights
Nov 23, 2009 |
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Researchers from the University of California, San Diego recently offered the sharpest-yet picture of how core biochemical pathways in skeletal muscle cells and fat cells are altered in people who suffer from ...
Are teenagers wired differently than adults?
Medicine & Health / Psychology & Psychiatry
Nov 17, 2009 |
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Parents have long suspected that the brains of their teenagers function differently than those of adults. With the advent of magnetic resonance imaging, or MRI, we have begun to appreciate how the brain continues to develop ...
Wistar researchers show targeting 'normal' cells in tumors slows growth
Nov 16, 2009 |
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Targeting the normal cells that surround cancer cells within and around a tumor is a strategy that could greatly increase the effectiveness of traditional anti-cancer treatments, say researchers at The Wistar Institute.
'Cross-talk' mechanism contributes to colorectal cancer
Nov 13, 2009 |
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Researchers at the University of Wisconsin-Madison School of Medicine and Public Health have identified a molecular mechanism that allows two powerful signaling pathways to interact and begin a process leading to colorectal ...
Paradoxical protein might prevent cancer
Nov 13, 2009 |
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(PhysOrg.com) -- One difficulty with fighting cancer cells is that they are similar in many respects to the body's stem cells. By focusing on the differences, researchers at Karolinska Institutet have found a new way of tackling ...
Antitumor activity of nutlin-3 in neuroblastoma with wild-type p53
Nov 10, 2009 |
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The small-molecule inhibitor nutlin-3 may be a viable treatment option for neuroblastoma patients with wild-type p53 activity, according to a new study published online November 10 in the Journal of the National Cancer In ...
Researchers to develop novel drug detection technology using software that acts like a robotic scientist
Chemistry / Analytical Chemistry
Nov 09, 2009 |
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(PhysOrg.com) -- Every time a person snorts cocaine, it doesn’t just go to his or her head: It also provokes a response in the immune system, creating special biomolecules that may serve as a permanent record of each exposure.
Tapeworm Drug May Hold Promise For Colon Cancer, Future Research
Nov 04, 2009 |
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(PhysOrg.com) -- Duke University Medical Center researchers have discovered an already-FDA-approved compound that can effectively “silence” a cell receptor shown to interfere with chemotherapy.
Two-In-One Punch Knocks Out Drug Resistant Cancer Cells
Nanotechnology / Bio & Medicine
Nov 04, 2009 |
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(PhysOrg.com) -- Cancer cells, like bacteria, can develop resistance to drug therapy, leading to relapse of disease. One approach showing promise in overcoming multidrug resistance in tumors is to combine two different anticancer ...
Researcher studies blood vessels that feed tumors
Nov 03, 2009 |
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(PhysOrg.com) -- Federal stimulus funding helps Cornell researchers create tiny 3-D models of tumors to mimic conditions necessary for the development of vascular systems by tumors.
Stress-induced changes in brain circuitry linked to cocaine relapse
Oct 30, 2009 |
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(PhysOrg.com) -- Stress-evoked changes in circuits that regulate serotonin in certain brain regions can precipitate a low mood and a relapse in cocaine-seeking.
JAX publishes online tool for exploring autoimmune disease gene networks
Oct 29, 2009 |
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Currently, 5-8% of the U.S. population is afflicted with an autoimmune disease. Many of these are chronic and require life-long care. Moreover, different autoimmune diseases aggregate within a single family, ...
Researchers use drug-radiation combo to eradicate lung cancer
Oct 29, 2009 |
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Researchers at UT Southwestern Medical Center have eliminated non-small cell lung (NSCL) cancer in mice by using an investigative drug called BEZ235 in combination with low-dose radiation.
