News tagged with pathway
Singapore scientists discover widely sought molecular key to understanding p53 tumor suppressor gene
Oct 13, 2009 |
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Scientists at the Singapore Immunology Network (SIgN) have determined how the master gene regulator p53 could switch a gene in a cell "on" or "off" by recognizing specific sequences of nucleotides in the gene's DNA.
Too much of a good thing? Scientists explain cellular effects of vitamin A overdose and deficiency
Oct 08, 2009 |
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If a little vitamin A is good, more must be better, right? Wrong! New research published online in the FASEB Journal shows that vitamin A plays a crucial role in energy production within cells, explaining why too much or too ...
African American lung cancer patients may have different response to new cancer-fighting drugs
Oct 07, 2009 |
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Clinical research out of University Hospitals Case Medical Center has found that African Americans with a common form of lung cancer have a lower frequency of drug-sensitizing genetic mutations, which may impact response ...
New approach for growing bone
Oct 07, 2009 |
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The natural cycle of building bone to maintain skeletal strength and then breaking it down for the body's calcium needs is delicately balanced, but diseases like osteoporosis break down too much bone without adequate bone ...
Researchers identify gene with possible link to infertility in mice
Oct 02, 2009 |
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Virginia Commonwealth University researchers have identified the role of a gene in regulating molecular signals involved with ovarian follicle development, which may one day help shed light on some of the causes of fertility ...
Duke/Singapore scientists find new way to classify gastric cancers
Oct 02, 2009 |
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An international team of scientists has discovered a new way to classify stomach cancers, and researchers say it may be an important step toward designing more effective treatments and improving long-term survival.
The making of the male brain (estrogen required)
Oct 01, 2009 |
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Territorial behavior in male mice might be linked to more "girl-power" than ever suspected, according to new findings at UCSF. For the first time, researchers have identified networks of nerve cells in the brain that are ...
Scientists discover clues to what makes human muscle age
Sep 30, 2009 |
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(PhysOrg.com) -- A study led by researchers at the University of California, Berkeley, has identified critical biochemical pathways linked to the aging of human muscle. By manipulating these pathways, the ...
New drug shows promise in the fight against malignant melanoma
Sep 29, 2009 |
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(PhysOrg.com) -- Gavin Robertson is not a man who uses the word ‘hate’ lightly, but he makes no secret of his desire to slay the dragon that is malignant melanoma.
Scientists get detailed glimpse of chemoreceptor architecture in bacterial cells
Sep 24, 2009 |
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Using state-of-the-art electron microscopy techniques, a team led by researchers from Caltech has for the first time visualized and described the precise arrangement of chemoreceptors—the receptors that sense ...
Figuring out the heads or tails decision in regeneration
Sep 14, 2009 |
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Amputations trigger a molecular response that determines if a head or tail will be regrown in planaria, a flatworm commonly studied for its regenerative capabilities. Until now, no molecular connection between wounding and ...
Key Brain Receptors Linked To Learning and Memory Decrease with Age
Medicine & Health / Neuroscience
Sep 11, 2009 |
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(PhysOrg.com) -- Scientists studying cognitive decline that accompanies aging have been interested in nicotinic receptors, part of a key neural pathway that not only enhances learning and memory skills but ...
RNA interference found in budding yeasts
Sep 11, 2009 |
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Some budding yeast species have the ability to silence genes using RNA interference (RNAi). Until now, most researchers thought that no budding yeasts possess the RNAi pathway because Saccharomyces cerevisiae, the protoypical ...
Plants on Steroids: Key Missing Link Discovered
Sep 08, 2009 |
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(PhysOrg.com) -- Researchers at the Carnegie Institution's Department of Plant Biology have discovered a key missing link in the so-called signaling pathway for plant steroid hormones (brassinosteroids). Many important signaling ...
Lapatinib shows minimal effect against liver cancer
Sep 08, 2009 |
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Use of the molecularly targeted agent lapatinib to delay tumor growth and improve the survival of patients with inoperable hepatocellular carcinoma, or liver cancer, only benefited certain subgroups of patients. While results ...
