Beef peptides block bitter tastes

From burgers to steaks, beef has a long history of being a delicious part of dinner. But what if that pleasant experience of eating beef could extend beyond the dinner plate? Now, one group reports in ACS' Journal of Agricultural ...

Increasing crop resistance to pathogens

We all know that animals have an immune system - but plants have systems to fight infection too. Plant cells have receptor proteins which bind with parts of a pathogen. These receptor proteins are located on the surface of ...

Immunoproteasome crystal structure determined

Like a shredder, the immunoproteasome cuts down proteins into peptides that are subsequently presented on the cellular surface. The immune system can distinguish between self and nonself peptides and selectively kills cells ...

Researchers block morphine's itchy side effect

Itching is one of the most prevalent side effects of powerful, pain-killing drugs like morphine, oxycodone and other opioids. The opiate-associated itch is so common that even women who get epidurals for labor pain often ...

Understanding the APJ Receptor Binding Site

(PhysOrg.com) -- Apelin is a recently discovered peptide that binds to the apelin (or APJ) G-protein-coupled receptor. Apelin-13 (NH2-QRPRLSHKGPMPF-COOH), one of several cleavage products of the proprotein form of the apelin ...

How to get obese mice moving -- and cure their diabetes

Mice lacking the fat hormone leptin or the ability to respond to it become morbidly obese and severely diabetic—not to mention downright sluggish. Now, a new study in the June Cell Metabolism shows that blood sugar control ...

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