Peering into a more 'human' petri dish

Cell culture media, the cocktail of chemicals and nutrients that keep cells alive and thriving in a dish, have been an essential tool of biology for more than 70 years. Remarkably, the composition of these potions hasn't ...

From blank round to a potently active substance?

A long-forgotten candidate for antiviral therapy is undergoing a renaissance: Since the 1970s, the small molecule CMA has been considered a potent agent against viral infections, yet it was never approved for clinical use. ...

New class of drugs for the reversible inhibition of proteasomes

As the "recycling plant" of the cell, the proteasome regulates vitally important functions. When it is inhibited, the cell chokes on its own waste. Cancer cells, in particular, are very sensitive because they need the proteasome ...