News tagged with pi3k
Metastatic breast cancer hitches a free ride from the immune system
Inflammatory breast cancer (IBC) is the most lethal form of breast cancer . It spreads easily through the lymphatic and blood vessels, forming metastasis which can lead to multi-organ failure. New research published in BioMed ...
Feb 10, 2012 |
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New breast cancer model of mutant PI3K recapitulates features of human breast cancer
Scientists from the Friedrich Miescher Institute for Biomedical Research have shown that a mutation in the lipid kinase PI3K, which occurs in about 30% of human breast cancers, itself evokes different forms ...
Jul 12, 2011 |
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Targeted agent addition to herceptin has positive effect on metastatic HER-2 breast cancer
Adding Afinitor to Herceptin, the main treatment for HER2-positive metastatic breast cancer, helps some women with disease that has been resistant to previous Herceptin-based therapies, according to a study led by researchers ...
Jul 08, 2011 |
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Study provides molecular rationale for combining targeted agents to treat breast cancer
A new study by Ohio State University cancer researchers provides a rational for treating breast cancer by combining two kinds of targeted agents, one that inhibits an overactive, cancer-causing pathway in cancer cells and ...
Jan 14, 2011 |
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Estrogen receptor status of HER2+ breast cancer correlates with response to anti-HER therapies
An international team of researchers has discovered molecular evidence that may explain why some women with HER2 over-expressing breast cancer do not respond to drugs designed to target this important molecule.
May 06, 2010 |
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Discovery opens door to new treatments for prostate, brain and skin cancers
Researchers at the Lady Davis Institute for Medical Research of the Jewish General Hospital and McGill University in Montreal have discovered a previously unsuspected link between two different genetic pathways which suppress ...
Jan 07, 2010 |
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Researchers use drug-radiation combo to eradicate lung cancer
Researchers at UT Southwestern Medical Center have eliminated non-small cell lung (NSCL) cancer in mice by using an investigative drug called BEZ235 in combination with low-dose radiation.
Oct 29, 2009 |
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Cell pathway on overdrive prevents cancer response to dietary restriction
Whitehead Institute researchers have pinpointed a cellular pathway that determines whether cancerous tumors respond to dietary restriction during their development.
Mar 11, 2009 |
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