News tagged with pluripotency
Parkinson's disease: Study of live human neurons reveals the disease's genetic origins
Parkinson's disease researchers at the University at Buffalo have discovered how mutations in the parkin gene cause the disease, which afflicts at least 500,000 Americans and for which there is no cure.
Feb 07, 2012 |
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Neurons from stem cells could replace mice in botulinum test
(PhysOrg.com) -- Using lab-grown human neurons, researchers from the University of Wisconsin-Madison have devised an effective assay for detecting botulinum neurotoxin, the agent widely used to cosmetically smooth the wrinkles ...
Feb 06, 2012 |
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Stem cells could drive hepatitis research forward
Hepatitis C, an infectious disease that can cause inflammation and organ failure, has different effects on different people. But no one is sure why some people are very susceptible to the infection, while ...
Feb 01, 2012 |
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Cambridge team first to grow smooth muscle cells from patient skin cells
A Cambridge University research team has for the first time discovered a method of generating different types of vascular smooth muscle cells (SMCs) - the cells which make up the walls of blood vessels - using cells from ...
Medicine & Health / Cardiology
Jan 26, 2012 |
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Alzheimer's neurons induced from pluripotent stem cells
Led by researchers at the University of California, San Diego School of Medicine, scientists have, for the first time, created stem cell-derived, in vitro models of sporadic and hereditary Alzheimer's disease ...
Medicine & Health / Neuroscience
Jan 25, 2012 |
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Therapeutically useful stem cell derivatives in need of stability
Human stem cells capable of giving rise to any fetal or adult cell type are known as pluripotent stem cells. It is hoped that such cells, the most well known being human embryonic stem cells (hESCs), can be used to generate ...
Jan 24, 2012 |
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Scientists report first step in strategy for cell replacement therapy in Parkinson's disease
Induced pluripotent stem cells (iPSC) are a promising avenue for cell replacement therapy in neurologic diseases. For example, mouse and human iPSCs have been used to generate dopaminergic (DA) neurons that improve symptoms ...
Jan 24, 2012 |
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Study unlocks origins of blood stem cells
A research team led by Nancy Speck, PhD, professor of Cell and Developmental Biology at the Perelman School of Medicine at the University of Pennsylvania, has discovered a molecular marker for the immediate ...
Dec 09, 2011 |
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Researchers develop safe way to repair sickle cell disease genes
Researchers at the Salk Institute for Biological Studies have developed a way to use patients' own cells to potentially cure sickle cell disease and many other disorders caused by mutations in a gene that ...
Dec 07, 2011 |
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Scalable amounts of liver and pancreas precursor cells created using new stem cell production method
Scientists in Canada have overcome a key research hurdle to developing regenerative treatments for diabetes and liver disease with a technique to produce medically useful amounts of endoderm cells from human pluripotent stem ...
Dec 02, 2011 |
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Bush embryonic stem cell lines different from newly derived cell lines
Established human embryonic cell lines, including those approved for federal research funding under former President George W. Bush, are different than newly derived human embryonic stem cell lines, according to a study by ...
Dec 01, 2011 |
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International initiative to address safety issues in stem cell therapy
An international study, published today in the prestigious journal Nature Biotechnology, reveals more about human pluripotent stem cells and their genetic stability and has important implications for the development of the ...
Nov 28, 2011 |
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Researchers uncover mechanism that regulates human pluripotent stem cell metabolism
Human pluripotent stem cells, which can develop into any cell type in the body, rely heavily on glycolysis, or sugar fermentation, to drive their metabolic activities.
Nov 15, 2011 |
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Lab-made skin cells will aid transplantation, cancer, drug discovery research
The pigmented cells called melanocytes aren't just for making freckles and tans. Melanocytes absorb ultraviolet light, protecting the skin from the harmful effects of the sun. They also are the cells that ...
Oct 26, 2011 |
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Scientists find stem cell reprogramming technique is safer than previously thought
Stem cells made by reprogramming patients' own cells might one day be used as therapies for a host of diseases, but scientists have feared that dangerous mutations within these cells might be caused by current reprogramming ...
Oct 06, 2011 |
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