News tagged with polymerase iii
Molecule stops DNA replication in its tracks
Biology /
Oct 20, 2008 |
4 / 5 (3) |
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(PhysOrg.com) -- When a dividing cell duplicates its genetic material, a molecular machine called a sliding clamp travels along the DNA double helix, tethering the proteins that perform the replication. Researchers ...
E. coli discovery could lead to new antibacterial target
Jul 29, 2008 |
4.5 / 5 (4) |
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Northeastern University scientists have discovered a new and unique DNA binding property of a protein in E. coli. Penny J. Beuning, Assistant Professor in the Department of Chemistry and Chemical Biology, spent the last two ...
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Pol3 mutation disrupts organ growth
Biology /
Nov 27, 2007 |
5 / 5 (2) |
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The cellular mechanism that turns DNA into all of the thousands of proteins that make up a human body is itself both intricate and interesting. A key player in the process—called transcription—is the enzyme RNA polymerase ...
Coming together: tDNAs, RNA pol III and chromatid cohesion
Sep 02, 2007 |
3.7 / 5 (3) |
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In the September 1st issue of G&D, Drs. Rudra Dubey and Marc Gartenberg (UMDNJ) reveal a surprising new role for tDNAs and RNA polymerase III-associated proteins in sister chromatid cohesion.
Bird flu leaves the nest -- adapting to a new host
Aug 26, 2009 |
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Current research suggests that viral polymerase may provide a new therapeutic target for host-adapted avian influenza. The related report by Gabriel et al, "Spread of Infection and Lymphocyte Depletion in Mice Depends on ...
Molecular typesetting -- proofreading without a proofreader
Jun 23, 2009 |
5 / 5 (1) |
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Researchers at the Universities of Leeds and Bristol (UK) have developed a model of how errors are corrected whilst proteins are being built.
How RNA polymerase II gets the go-ahead for gene transcription
Oct 09, 2009 |
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All cells perform certain basic functions. Each must selectively transcribe parts of the DNA that makes up its genome into RNAs that specify the structure of proteins. The set of proteins synthesized by a cell in turn determines ...
New piece found in the puzzle of epigenetics
Jun 16, 2009 |
5 / 5 (8) |
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For many years scientists have known that the numerous biological functions of an organism are not regulated solely by the DNA sequence of its genes: Superordinate regulatory mechanisms exist that contribute to determining ...
Clearing jams in copy machinery
Sep 19, 2005 |
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Bacteria and humans use a number of tools to direct perhaps the most important function in cells -- the accurate copying of DNA during cell division. New research published this week in Molecular Cell from the laboratory ...
Researchers Reveal Structure of Key Genetic Proofreading Protein
Jun 05, 2009 |
5 / 5 (2) |
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(PhysOrg.com) -- Nature might abhor a vacuum, but it loves a backup plan. In living organisms, physiological systems are kept under tight control by hierarchies of organic safety catches and emergency releases, ...
TRAPping proteins that work together inside living cells
Jun 15, 2009 |
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DNA might be the blueprint for living things, but proteins are the builders. Researchers trying to understand how and which proteins work together have developed a new crosslinking tool that is small and unobtrusive ...
Faster, more cost-effective DNA test for crime scenes, disease diagnosis
Chemistry / Analytical Chemistry
Jul 08, 2009 |
4 / 5 (1) |
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Scientists in Japan are reporting development of a faster, less expensive version of the fabled polymerase chain reaction (PCR) a DNA test widely used in criminal investigations, disease diagnosis, biological ...
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