News tagged with polymerase
Research into possible Woodchester wild cat finds no cat DNA on deer
Extensive DNA tests by experts at the University of Warwick on two deer carcasses found in Gloucestershire have not found any indication of a big cat presence.
Feb 01, 2012 |
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Study uncovers how DNA unfolds for transcription
(PhysOrg.com) -- The human genome contains some 3 billion base pairs that are tightly compacted into the nucleus of each cell. If a DNA strand were the thickness of a human hair, the entire human genome would ...
Jan 17, 2012 |
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Simple blood test in the first trimester predicts fetal gender
A new research study published in the January 2012 edition of The FASEB Journal describes findings that could lead to a non-invasive test that would let expecting mothers know the sex of their baby as early as the first ...
Jan 03, 2012 |
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Transcriptional elongation control takes on new dimensions
Life is complicated enough, so you can forgive the pioneers of DNA biology for glossing over transcriptional elongation control by RNA polymerase II, the quick and seemingly bulletproof penultimate step in ...
Dec 22, 2011 |
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Researchers demonstrate new DNA detection technique
A team of researchers from the University of Notre Dame have demonstrated a novel DNA detection method that could prove suitable for many real-world applications.
Dec 16, 2011 |
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Nanoparticles and Mini-NMR point the way to personalized cancer therapy
(PhysOrg.com) -- With the advent of targeted drug therapy for treating cancer, it has become clear that an important predictor of success of these therapies is whether such a drug is reaching its target in the patient. The ...
Nanotechnology / Bio & Medicine
Nov 21, 2011 |
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Researchers find way to screen for broad range of cancer-causing genetic changes
Researchers in the United States have shown, for the first time, that it is possible to screen cancer patients for a broad range of cancer-causing genetic mutations as part of normal clinical practice. By identifying patients' ...
Nov 09, 2011 |
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Test identifies Red Angus carriers of bone disease
A new test that detects a rare and deadly bone disorder in Red Angus is now available to cattle producers, thanks to U.S. Department of Agriculture (USDA) scientists.
Sep 29, 2011 |
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Structure of a molecular copy machine: How mitochondrial genes are transcribed
Mitochondria are compartments within cells and have their own DNA. The key protein required for the expression of the genetic information in this DNA is the mitochondrial RNA polymerase enzyme. Its three-dimensional structure ...
Sep 26, 2011 |
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CSI: PCR-free techniques ID the most active microbes on the scene
Anyone who has watched one of the CSI: Crime Scene Investigation television shows knows that PCR (Polymerase Chain Reaction) is a technology used to amplify the tiniest samples of DNA into forensic evidence ...
Sep 21, 2011 |
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Dundee researchers make gene breakthrough
Researchers at the University of Dundee have made a significant breakthrough in understanding how human cells decode genes important for cell growth and multiplication.
Sep 16, 2011 |
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A better test for a potato pest
A U.S. Department of Agriculture (USDA) scientist has created a new weapon in the war being waged against the potato cyst nematode-a diagnostic test that identifies the type of nematode infesting a grower's field.
Aug 23, 2011 |
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Olaparib shows promise in treating ovarian cancer, even without BRCA mutations
The PARP inhibitor, olaparib, that has shown promise in women with an inherited mutation in their BRCA1 or BRCA2 gene (accounting for about 5-10% of breast and ovarian cancer cases), has, for the first time, been shown to ...
Aug 21, 2011 |
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Researchers reveal a new mechanism of genomic instability
Researchers at NYU School of Medicine have discovered the cellular mechanisms that normally generate chromosomal breaks in bacteria such as E. coli. The study's findings are published in the August 18 issue of the journal ...
Aug 18, 2011 |
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Technology reveals citrus greening-infected trees
U.S. Department of Agriculture (USDA) scientists are using a technology known as "Fourier transform infrared-attenuated total reflection" (FTIR-ATR) spectroscopy to rapidly identify with 95 percent accuracy citrus plant leaves ...
Aug 08, 2011 |
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Polymerase
A polymerase (EC 2.7.7.6/7/19/48/49) is an enzyme whose central function is associated with polymers of nucleic acids such as RNA and DNA. The primary function of a polymerase is the polymerization of new DNA or RNA against an existing DNA or RNA template in the processes of replication and transcription. In association with a cluster of other enzymes and proteins, they take nucleotides from solvent, and catalyse the synthesis of a polynucleotide sequence against a nucleotide template strand using base-pairing interactions.
It is an accident of history that the enzymes responsible for the catalytic production of other biopolymers are not also referred to as polymerases.
One particular polymerase, from the thermophilic bacterium, Thermus aquaticus (Taq) (PDB 1BGX, EC 2.7.7.7) is of vital commercial importance due to its use in the polymerase chain reaction, a widely used technique of molecular biology.
Other well-known polymerases include:
For more information about Polymerase, read the full article at
Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.
