Parasites thought only to infect tropical coral reefs have been discovered in a large variety of creatures in cold marine ecosystems along the Northeast Pacific, according to new research from University of British Columbia ...
Plants & Animals
Apr 11, 2024
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4
Brandt Eichman and Walter Chazin, professors of biochemistry, have worked together to provide a better understanding of how exactly DNA replication is initiated in eukaryotes. Using Vanderbilt's state-of-the-art instrumentation ...
Cell & Microbiology
Mar 18, 2024
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7
A pair of chemists at the University of Groningen in the Netherlands, has observed communication between rotors in a molecular motor. In their study, reported in the Journal of the American Chemical Society, Carlijn van Beek ...
The secrets of photosynthesis have been discovered at the atomic level, shedding important new light on this plant super-power that greened the Earth more than a billion years ago.
Plants & Animals
Mar 4, 2024
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44
For life on Earth, it is essential that plants carry out photosynthesis and ultimately produce oxygen and chemical energy with the help of sunlight. Researchers from Göttingen and Hannover have now succeeded for the first ...
Plants & Animals
Mar 4, 2024
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1
Researchers led by University of Tsukuba have discovered rdxPolA, a putative DNA polymerase involved in replicating ancestral mitochondrial genomes, in diverse eukaryotic lineages. Based on the phylogenetic distribution of ...
Evolution
Feb 28, 2024
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0
A technique can determine for the first time how frequently, and exactly where, a molecular event called "backtracking" occurs throughout the genetic material (genome) of any species, a new study shows.
Biotechnology
Feb 9, 2024
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286
In a new Nature Communications study, researchers have explored the construction of genetic circuits on single DNA molecules, demonstrating localized protein synthesis as a guiding principle for dissipative nanodevices, offering ...
Scientists have been making nanoparticles out of DNA strands for two decades, manipulating the bonds that maintain DNA's double-helical shape to sculpt self-assembling structures that could someday have jaw-dropping medical ...
Bio & Medicine
Feb 6, 2024
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48
The intricate process of duplicating genetic information, referred to as DNA replication, lies at the heart of the transmission of life from one cell to another and from one organism to the next. This happens by not just ...
Cell & Microbiology
Dec 20, 2023
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123
A polymerase (EC 2.7.7.6/7/19/48/49) is an enzyme whose central function is associated with polymers of nucleic acids such as RNA and DNA. The primary function of a polymerase is the polymerization of new DNA or RNA against an existing DNA or RNA template in the processes of replication and transcription. In association with a cluster of other enzymes and proteins, they take nucleotides from solvent, and catalyse the synthesis of a polynucleotide sequence against a nucleotide template strand using base-pairing interactions.
It is an accident of history that the enzymes responsible for the catalytic production of other biopolymers are not also referred to as polymerases.
One particular polymerase, from the thermophilic bacterium, Thermus aquaticus (Taq) (PDB 1BGX, EC 2.7.7.7) is of vital commercial importance due to its use in the polymerase chain reaction, a widely used technique of molecular biology.
Other well-known polymerases include:
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