News tagged with polymerase


Gene transcribing machine takes halting, backsliding trip along the DNA

Gene transcribing machine takes halting, backsliding trip along the DNA

Chemistry / Biochemistry

created Jul 30, 2009 | popularity 5 / 5 (4) | comments 1

(PhysOrg.com) -- The body's nanomachines that read our genes don't run as smoothly as previously thought, according to a new study by University of California, Berkeley, scientists.


Monitoring Cancer Cell Changes With Quantum Dots

Nanotechnology / Bio & Medicine

created Jul 23, 2009 | popularity 5 / 5 (1) | comments 0

One of the earliest events that changes a normal cell into a malignant one is known as deoxyribonucleic acid (DNA) hypermethylation, a biochemical alteration that inactivates critical tumor-suppressor genes. A team of investigators ...


'Sloppier copier' surprisingly efficient

Biology / Cell & Microbiology

created Jul 15, 2009 | popularity 4.3 / 5 (4) | comments 3

The "sloppier copier" discovered by USC biologists is also the best sixth man in the DNA repair game, an article in the journal Nature shows.


One secret to how TB sticks with you

Biology / Cell & Microbiology

created Jul 09, 2009 | popularity 3 / 5 (2) | comments 0

Mycobacterium tuberculosis is arguably the world's most successful infectious agent because it knows how to avoid elimination by slowing its own growth to a crawl. Now, a report in the July 10 issue of the journal Cell, ...


Faster, more cost-effective DNA test for crime scenes, disease diagnosis

Faster, more cost-effective DNA test for crime scenes, disease diagnosis

Chemistry / Analytical Chemistry

created Jul 08, 2009 | popularity 4 / 5 (1) | comments 0

Scientists in Japan are reporting development of a faster, less expensive version of the fabled polymerase chain reaction (PCR) a DNA test widely used in criminal investigations, disease diagnosis, biological ...


Ultrasensitive detector promises improved treatment of viral respiratory infections

Ultrasensitive detector promises improved treatment of viral respiratory infections

Chemistry / Analytical Chemistry

created Jun 29, 2009 | popularity not rated yet | comments 0

(PhysOrg.com) -- A Vanderbilt chemist and a biomedical engineer have teamed up to develop a respiratory virus detector that is sensitive enough to detect an infection at an early stage, takes only a few minutes ...


Molecular typesetting -- proofreading without a proofreader

Biology / Cell & Microbiology

created Jun 23, 2009 | popularity 5 / 5 (1) | comments 0

Researchers at the Universities of Leeds and Bristol (UK) have developed a model of how errors are corrected whilst proteins are being built.


New piece found in the puzzle of epigenetics

Biology / Cell & Microbiology

created Jun 16, 2009 | popularity 5 / 5 (8) | comments 0

For many years scientists have known that the numerous biological functions of an organism are not regulated solely by the DNA sequence of its genes: Superordinate regulatory mechanisms exist that contribute to determining ...


TRAPping proteins that work together inside living cells

TRAPping proteins that work together inside living cells

Biology / Cell & Microbiology

created Jun 15, 2009 | popularity not rated yet | comments 0

DNA might be the blueprint for living things, but proteins are the builders. Researchers trying to understand how and which proteins work together have developed a new crosslinking tool that is small and unobtrusive ...


Researchers Reveal Structure of Key Genetic Proofreading Protein

Researchers Reveal Structure of Key Genetic Proofreading Protein

Chemistry / Biochemistry

created Jun 05, 2009 | popularity 5 / 5 (2) | comments 0

(PhysOrg.com) -- Nature might abhor a vacuum, but it loves a backup plan. In living organisms, physiological systems are kept under tight control by hierarchies of organic safety catches and emergency releases, ...


Rapid approach to identify influenza A virus mutations and drug resistance developed

Medicine & Health / Research

created May 28, 2009 | popularity not rated yet | comments 0

Genome Institute of Singapore scientists, led by Christopher Wong, Ph.D., have developed a novel approach to uncover the complete sequence of any influenza A virus, including H1NI, with just a quick nasal swab or nasal pharyngeal ...


FluChip technology licensed to combat deadly flu virus

Medicine & Health / Research

created Apr 28, 2009 | popularity 1 / 5 (1) | comments 0

InDevR, a small biotech company in Boulder, CO, announced today that they have licensed the FluChip technology from the University of Colorado. The FluChip was invented by a joint team of scientists at the University of ...


Bacteria are models of efficiency

Biology /

created Feb 04, 2009 | popularity 4 / 5 (1) | comments 0

The bacterium Escherichia coli, one of the best-studied single-celled organisms around, is a master of industrial efficiency. This bacterium can be thought of as a factory with just one product: itself. It exists to make c ...


Researchers study virus with unusual properties

Researchers study virus with unusual properties

Biology /

created Dec 08, 2008 | popularity 4.7 / 5 (14) | comments 0

(PhysOrg.com) -- A team of researchers from Penn State University and the University of Chicago has uncovered clues that may explain how and why a particular virus, called N4, injects an unusual substance ...


How 'molecular machines' kick start gene activation revealed

Biology /

created Nov 06, 2008 | popularity 4.8 / 5 (4) | comments 0

How 'molecular machines' inside cells swing into action to activate genes at different times in a cell's life is revealed today in new research published in Molecular Cell.