News tagged with pore complex

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Biologists reveal structure of cell nucleus 'gatekeeper'

Biologists reveal structure of cell nucleus 'gatekeeper'

Biology / Cell & Microbiology

created Oct 27, 2009 | popularity 4 / 5 (5) | comments 6

(PhysOrg.com) -- Biologists led by associate professor Thomas Schwartz (MIT) have worked out a rudimentary architectural plan for the nuclear pore complex (NPC), the gatekeeper of the cell's nucleus.


Come on in: Nuclear barrier less restrictive than expected in new cells

Chemistry / Biochemistry

created Oct 06, 2009 | popularity not rated yet | comments 0

When it comes to the two basic types of cells, prokaryotes and eukaryotes, compartmentalization is everything. Prokaryotes are evolutionarily ancient cells that only have a membrane surrounding their outer boundary, while ...


'Promiscuous' protein interactions found in the nuclear pore complex

Biology / Cell & Microbiology

created Sep 29, 2009 | popularity 5 / 5 (1) | comments 0

(PhysOrg.com) -- The NPC is the only way in or out of a cell's nucleus. It plays a key role in cellular metabolism and signaling, and any malfunction in these pores can have lethal consequences. Now new research reveals further ...


Solving the Nuclear Pore Puzzle

Solving the Nuclear Pore Puzzle

Chemistry / Biochemistry

created Aug 19, 2009 | popularity not rated yet | comments 0

(PhysOrg.com) -- Computational biochemist Frank Alber compares determining the architecture of a macromolecular machine to solving a jigsaw puzzle.


New research supports model for nuclear pore complex

Biology / Cell & Microbiology

created Aug 18, 2009 | popularity not rated yet | comments 0

(PhysOrg.com) -- To protect their DNA, cells in higher organisms are very choosy about what they allow in and out of their nuclei, where the genes reside. Guarding access is the job of transport machines called nuclear pore ...


Research suggests core nuclear pore elements shared by all eukaryotes

Chemistry / Biochemistry

created Jul 13, 2009 | popularity 5 / 5 (1) | comments 0

(PhysOrg.com) -- For perhaps 1.8 billion years after life first emerged on Earth, a sort of evolutionary writer’s block stalled the development of organisms more complicated than single cells. Then, a burst of experimental ...


Researchers construct a device that mimics one of nature’s key transport machines

Researchers construct a device that mimics one of nature's key transport machines

Biology /

created Jan 06, 2009 | popularity 4.7 / 5 (7) | comments 0

(PhysOrg.com) -- To help protect its genes, a cell is highly selective about what it allows to move in and out of its nucleus. Yet that choosiness is regulated by just a thin barrier, perforated with tiny ...


Structural study backs new model for the nuclear pore complex

Structural study backs new model for the nuclear pore complex

Biology /

created Dec 24, 2008 | popularity 4.5 / 5 (2) | comments 0

(PhysOrg.com) -- In higher organisms, the genetic material is confined and protected in the cell nucleus. In order for a healthy cell to function, the DNA must send manufacturing orders through the double ...