News tagged with pore
Biologists reveal structure of cell nucleus 'gatekeeper'
Oct 27, 2009 |
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(PhysOrg.com) -- Biologists led by associate professor Thomas Schwartz (MIT) have worked out a rudimentary architectural plan for the nuclear pore complex (NPC), the gatekeeper of the cell's nucleus.
Come on in: Nuclear barrier less restrictive than expected in new cells
Oct 06, 2009 |
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When it comes to the two basic types of cells, prokaryotes and eukaryotes, compartmentalization is everything. Prokaryotes are evolutionarily ancient cells that only have a membrane surrounding their outer boundary, while ...
'Promiscuous' protein interactions found in the nuclear pore complex
Sep 29, 2009 |
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(PhysOrg.com) -- The NPC is the only way in or out of a cell's nucleus. It plays a key role in cellular metabolism and signaling, and any malfunction in these pores can have lethal consequences. Now new research reveals further ...
Solving the Nuclear Pore Puzzle
Aug 19, 2009 |
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(PhysOrg.com) -- Computational biochemist Frank Alber compares determining the architecture of a macromolecular machine to solving a jigsaw puzzle.
New research supports model for nuclear pore complex
Aug 18, 2009 |
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(PhysOrg.com) -- To protect their DNA, cells in higher organisms are very choosy about what they allow in and out of their nuclei, where the genes reside. Guarding access is the job of transport machines called nuclear pore ...
Research suggests core nuclear pore elements shared by all eukaryotes
Jul 13, 2009 |
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(PhysOrg.com) -- For perhaps 1.8 billion years after life first emerged on Earth, a sort of evolutionary writer’s block stalled the development of organisms more complicated than single cells. Then, a burst of experimental ...
Research identifies 3-D structure of key nuclear pore building block
Jun 07, 2009 |
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The genome of complex organisms is stashed away inside each cell's nucleus, a little like a sovereign shielded from the threatening world outside. The genome cannot govern from its protective chamber, however, without knowing ...
Researchers create novel nanotechnique to sequence human genome
Nanotechnology / Bio & Medicine
Apr 15, 2009 |
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Since the human genome was sequenced six years ago, the cost of producing a high-quality genome sequence has dropped precipitously. More recently, the National Institutes of Health called for cutting the cost ...
The breakdown of barriers in old cells may hold clues to aging process
Biology /
Jan 22, 2009 |
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Like guards controlling access to a gated community, nuclear pore complexes are communication channels that regulate the passage of proteins and RNA to and from a cell's nucleus. Recent studies by researchers ...
Researchers construct a device that mimics one of nature's key transport machines
Biology /
Jan 06, 2009 |
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(PhysOrg.com) -- To help protect its genes, a cell is highly selective about what it allows to move in and out of its nucleus. Yet that choosiness is regulated by just a thin barrier, perforated with tiny ...
Structural study backs new model for the nuclear pore complex
Biology /
Dec 24, 2008 |
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(PhysOrg.com) -- In higher organisms, the genetic material is confined and protected in the cell nucleus. In order for a healthy cell to function, the DNA must send manufacturing orders through the double ...
Mitochondria could be a target for therapeutic strategy for Alzheimer's disease patients
Nov 05, 2008 |
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A study in the Sept. 21 on-line edition of Nature Medicine describes the function and interaction of a critical molecule involved in cell death in Alzheimer's disease patients. These new findings reveal that blocking this m ...
