News tagged with preexisting neutralizing

NIAID will not move forward with the PAVE 100 HIV Vaccine Trial

Medicine & Health / HIV & AIDS

Jul 17, 2008 | not rated yet | 0

After soliciting and considering broad input from the scientific and HIV advocacy communities, the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH), has determined ...

New strategy proposed for designing antibody-based HIV vaccine

Medicine & Health / HIV & AIDS

Jun 14, 2009 | not rated yet | 0

WHAT: Most vaccines that protect against viruses generate infection-fighting proteins called antibodies that either block infection or help eliminate the virus before it can cause disease. Attempts to create a vaccine that ...

New technology opens gateway to studying HIV-specific neutralizing antibodies

Medicine & Health / HIV & AIDS

Mar 16, 2009 | not rated yet | 0

Many scientists believe a vaccine that prevents HIV infection will need to stimulate the body to make neutralizing antibodies, infection-fighting proteins that prevent HIV from entering immune cells. Previous research has ...

Researchers induce HIV-neutralizing antibodies that recognize HIV-1 envelope protein, lipids

Medicine & Health / HIV & AIDS

Sep 01, 2009 | not rated yet | 0

For the first time, researchers have experimentally induced antibodies that neutralize HIV-1 and simultaneously recognize both HIV-1 envelope protein and lipids. The results were reported by U.S. Military HIV Research Program ...

Study offers insights into failed HIV-1 vaccine trial

Medicine & Health / HIV & AIDS

Jul 20, 2009 | 5 / 5 (1) | 1

Following the disbandment of the STEP trial to test the efficacy of the Merck HIV-1 vaccine candidate in 2007, the leading explanation for why the vaccine was ineffective - and may have even increased susceptibility to acquiring ...

HIV uses several strategies to escape immune pressure

Medicine & Health / HIV & AIDS

Sep 19, 2009 | 5 / 5 (3) | 0

A study of how HIV mutates in response to immune system pressure by Emory Vaccine Center researchers shows that the virus can take several escape routes, not one preferred route.

Scientists gain insight into HIV vaccine failure

Medicine & Health / HIV & AIDS

Jul 20, 2009 | 3.5 / 5 (4) | 0

A team of researchers from The Wistar Institute and the University of Pennsylvania reports new evidence refuting a popular hypothesis about the highly publicized failure in 2007 of the Merck STEP HIV vaccine study that cast ...

Scientists identify genetic link that may neutralize HIV

Medicine & Health / HIV & AIDS

Sep 04, 2008 | 4.5 / 5 (24) | 0

Scientists from the Gladstone Institute of Virology and Immunology (GIVI) and the National Institutes of Allergy and Infectious Diseases (NIAID) have identified a gene that may influence the production of antibodies that ...

Study sees need for standardized evaluation of antibody response to HIV-1

Medicine & Health / HIV & AIDS

Aug 07, 2008 | 4 / 5 (1) | 0

U.S. Military HIV Research Program (USMHRP) researcher Victoria R. Polonis, Ph.D., and colleagues released findings on a study of cross-clade neutralization patterns among HIV-1 strains from six major clades in the 5 Jun ...

New findings suggest strategy to help generate HIV-neutralizing antibodies

Medicine & Health / HIV & AIDS

Nov 19, 2009 | not rated yet | 0

New discoveries about anti-HIV antibodies may bring researchers a step closer to creating an effective HIV vaccine, according to a new paper co-authored by scientists at the Vaccine Research Center of the National Institute ...

Clinical trial will test new HIV/AIDS vaccine

Medicine & Health / HIV & AIDS

Apr 03, 2008 | 5 / 5 (1) | 0

A phase 1 clinical trial to test a novel HIV/AIDS vaccine has begun at Brigham and Women’s Hospital (BWH). This new vaccine aims to overcome the problem of preexisting immunity to common vaccine vectors, which is thought ...

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