News tagged with prion disease
The protein Srebp2 drives cholesterol formation in prion-infected neuronal cells
Nov 18, 2009 |
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Prions are causing fatal and infectious diseases of the nervous system, such as the mad cow disease (BSE), scrapie in sheep or Creutzfeldt-Jakob disease in humans. Scientists of Helmholtz Zentrum München and Technische Universität ...
Mutant proteins result in infectious prion disease in mice
Biology /
Dec 05, 2008 |
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A worldwide group of scientists has created an infectious prion disease in a mouse model, in a step that may help unravel the mystery of this progressive disease that affects the nervous system in humans and animals. The ...
Gene mutation alone causes transmissible prion disease
Medicine & Health / Neuroscience
Aug 26, 2009 |
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For the first time, Whitehead Institute researchers have shown definitively that mutations associated with prion diseases are sufficient to cause a transmissible neurodegenerative disease.
Species barrier may protect macaques from chronic wasting disease
Jul 30, 2009 |
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Data from an ongoing multi-year study suggest that people who consume deer and elk with chronic wasting disease (CWD) may be protected from infection by an inability of the CWD infectious agent to spread to people. The results ...
Sticky antibodies block prion disease
Biology /
Feb 12, 2009 |
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(PhysOrg.com) -- Antibodies that stick to a brain prion protein called PrP could be the key to treating prion diseases like variant CJD and preventing people accidentally exposed to prions from going on to ...
Impaired transport in neurons triggers prion disease
Aug 21, 2009 |
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A new study shows that nervous system integrity and axonal properties may play a key role in prion diseases. The findings, from researchers at the Rudolf Virchow Center and the Institute of Virology of the University of Würzburg, ...
Mouse model of prion disease mimics diverse symptoms of human disorder
Nov 26, 2008 |
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A comprehensive mouse model of inherited prion disease exhibits cognitive, motor, and neurophysiological deficits that bear a striking resemblance to the symptoms experienced by patients with the human version of "mad cow ...
