News tagged with prion infection


Protective pathway in stressed cells not so helpful when it comes to prions

Medicine & Health / Research

created Sep 15, 2008 | popularity 5 / 5 (2) | comments 0

Scientists at the National Institutes of Health (NIH) have discovered that an important cellular quality control mechanism may actually be toxic to some brain cells during prion infection. The research, published by Cell ...





Search results for prion infection


Prion infectivity found in white and brown fat tissues of mice

Biology /

created Dec 05, 2008 | popularity 4 / 5 (2) | comments 0

Researchers from the National Institutes of Health and the Scripps Research Institute have found novel prion infectivity in white and brown fat tissues of mice. The study appears December 5 in the open-access journal PLoS Pa ...


Levels of prion protein in brain may not be reliable marker for disease

Medicine & Health / Diseases

created Nov 30, 2007 | popularity 5 / 5 (4) | comments 0

Rapid diagnostic testing used to check for the presence of prion diseases such as “mad cow disease” might fail to identify some highly infectious samples, researchers have found. Currently, scanning beef or other meat products ...


Prions link cholesterol to neurodegeneration

Biology /

created Feb 12, 2008 | popularity 4.5 / 5 (2) | comments 0

Prion infection of neurons increases the free cholesterol content in cell membranes. A new study published in the online open access journal BMC Biology suggests that disturbances in membrane cholesterol may be the mechan ...


Lymph nodes can be key in spreading prion infectivity

Medicine & Health / Research

created Sep 25, 2007 | popularity 3.5 / 5 (2) | comments 0

Lymph nodes can be crucial for spreading low doses of infective prion agents -the pathogens responsible for conditions such as scrapie and Creutzfeldt-Jakob disease - into the nervous system, according to new research published ...


Sticky antibodies block prion disease

Sticky antibodies block prion disease

Biology /

created Feb 12, 2009 | popularity 5 / 5 (1) | comments 0

(PhysOrg.com) -- Antibodies that stick to a brain prion protein called PrP could be the key to treating prion diseases like variant CJD and preventing people accidentally exposed to prions from going on to ...


A novel approach in the molecular differentiation of prion strains

Biology /

created Aug 29, 2008 | popularity 5 / 5 (1) | comments 0

A team from the French Food Safety Agency, Lyon, France, has identified a prion protein characteristic that is unique to some natural but unusual sheep scrapie cases. This finding, reported August 29th in the open-access ...


Scientists develop new tests that identify lethal prion strains quickly and accurately

Biology /

created Dec 04, 2007 | popularity 3.5 / 5 (4) | comments 0

One of the new in vitro tests, called the Standard Scrapie Cell Assay, measures prion infectivity levels in a highly accurate and extremely rapid way, producing results in less than two weeks. The second test, called the ...


Gene mutation alone causes transmissible prion disease

Medicine & Health / Neuroscience

created Aug 26, 2009 | popularity 5 / 5 (1) | comments 0

For the first time, Whitehead Institute researchers have shown definitively that mutations associated with prion diseases are sufficient to cause a transmissible neurodegenerative disease.


Common soil mineral degrades the nearly indestructible prion

Biology /

created Jan 14, 2009 | popularity 5 / 5 (4) | comments 1

(PhysOrg.com) -- In the rogues' gallery of microscopic infectious agents, the prion is the toughest hombre in town.


The protein Srebp2 drives cholesterol formation in prion-infected neuronal cells

Chemistry / Biochemistry

created Nov 18, 2009 | popularity 4 / 5 (1) | comments 0

Prions are causing fatal and infectious diseases of the nervous system, such as the mad cow disease (BSE), scrapie in sheep or Creutzfeldt-Jakob disease in humans. Scientists of Helmholtz Zentrum München and Technische Universität ...



List of search results for prion infection