News tagged with prion protein

Scientists identify most lethal known species of prion protein

Scientists from the Florida campus of The Scripps Research Institute have identified a single prion protein that causes neuronal death similar to that seen in "mad cow" disease, but is at least 10 times more ...

Medicine & Health / Research

created Feb 09, 2012 | popularity 4.8 / 5 (9) | comments 2 | with audio podcast

Making memories last: Prion-like protein plays key role in storing long-term memories

Memories in our brains are maintained by connections between neurons called "synapses". But how do these synapses stay strong and keep memories alive for decades? Neuroscientists at the Stowers Institute for ...

Medicine & Health / Research

created Jan 27, 2012 | popularity 4.9 / 5 (14) | comments 1 | with audio podcast

New study shows prions able to jump between species more easily than thought

(PhysOrg.com) -- A group of French researchers has found that prions are more easily able to jump between species than has been previously thought. In their paper published in Science, they show that prions ...

Biology / Cell & Microbiology

created Jan 27, 2012 | popularity 4.8 / 5 (12) | comments 2 | with audio podcast report

Blood test for human form of mad cow disease developed

(Medical Xpress) -- Mad cow disease is serious business in the U.K., the human form, known as Creutzfeldt-Jakob after Hans Gerhard Creutzfeldt and Alfons Maria Jakob (CJD), who independently first described its existence ...

Medicine & Health / Diseases

created Jan 16, 2012 | popularity 4 / 5 (4) | comments 0 | with audio podcast report

New findings about the prion protein and its interaction with the immune system

(Medical Xpress) -- Scrapie is a neurodegenerative disease which can function as a model for other diseases caused by an accumulation of proteins resulting in tissue malformations (proteinpathies), such as ...

Medicine & Health / Research

created Dec 21, 2011 | popularity 5 / 5 (1) | comments 0

Protein sheds insight into vCJD

A protein linked to the immune system could play a key role in helping scientists understand how vCJD spreads throughout the body.

Medicine & Health / Research

created Dec 02, 2011 | popularity not rated yet | comments 0 | with audio podcast

Medical researchers discover hidden side of prion diseases

Medical researchers in Canada and the United States recently published their joint findings that fatal prion diseases, which include BSE or "mad cow disease," have a hidden signature.

Medicine & Health / Diseases

created Nov 30, 2011 | popularity 4 / 5 (1) | comments 0

Researchers discover possible key to degenerative nerve diseases

(Medical Xpress) -- Researchers at the University of Wisconsin-Madison and collaborators have discovered a powerful new protein in the eye of the fruit fly that may shed light on blinding diseases and other ...

Medicine & Health / Neuroscience

created Nov 17, 2011 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Alzheimer's might be transmissible in similar way as infectious prion diseases: study

The brain damage that characterizes Alzheimer's disease may originate in a form similar to that of infectious prion diseases such as bovine spongiform encephalopathy (mad cow) and Creutzfeldt-Jakob, according to newly published ...

Medicine & Health / Diseases

created Oct 04, 2011 | popularity 5 / 5 (3) | comments 1 | with audio podcast

'Good' prion-like proteins boost immune response

(Medical Xpress) -- A person's ability to battle viruses at the cellular level remarkably resembles the way deadly infectious agents called prions misfold and cluster native proteins to cause disease, UT Southwestern Medical ...

Medicine & Health / Research

created Aug 09, 2011 | popularity not rated yet | comments 0 | with audio podcast

Cellular stress can induce yeast to promote prion formation

It's a chicken and egg question. Where do the infectious protein particles called prions come from? Essentially clumps of misfolded proteins, prions cause neurodegenerative disorders, such as mad cow/Creutzfeld-Jakob disease, ...

Biology / Cell & Microbiology

created Jul 23, 2011 | popularity 5 / 5 (3) | comments 0 | with audio podcast

Study finds two gene classes linked to new prion formation

Unlocking the mechanisms that cause neurodegenerative prion diseases may require a genetic key, suggest new findings reported by University of Illinois at Chicago distinguished professor of biological sciences Susan Liebman.

Medicine & Health / Genetics

created May 26, 2011 | popularity not rated yet | comments 0 | with audio podcast

NIH study describes fast, sensitive blood test for human prion disease

Scientists from the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH), report that they have developed a method—10,000 times more sensitive than other methods—to ...

Medicine & Health / Diseases

created May 09, 2011 | popularity not rated yet | comments 0

Multitarget drugs against prion diseases

The central nervous systems of humans and cattle alike are attacked by prions (abnormal insoluble amyloidogenic proteins) when they suffer from Creutzfeldt–Jakob disease (CJD) or bovine spongiform encephalopathy ...

Chemistry / Biochemistry

created Mar 21, 2011 | popularity 5 / 5 (1) | comments 0

Mutant prions help cells foil harmful protein misfolding

Romping clumps of misfolded proteins are prime suspects in many neurological disorders including Alzheimer's, Parkinson's, and Creutzfeld-Jakob Disease. Those diseases are devastating and incurable, but a team of biologists ...

Biology / Cell & Microbiology

created Mar 20, 2011 | popularity 4 / 5 (1) | comments 0 | with audio podcast

PRNP

More reference expression data

PRNP (PRioN Protein (Creutzfeld-Jakob disease, Gerstmann-Sträussler-Scheinker syndrome, fatal familial insomnia)) is a gene that codes for a protein called the prion protein (PrP), which is expressed in the brain and several other tissues.

The human PRNP gene is located on the short (p) arm of chromosome 20 between the end (terminus) of the arm and position 12, from base pair 4,615,068 to base pair 4,630,233.

PRNP has also recently been designated CD230 (cluster of differentiation 230).

For more information about PRNP, read the full article at Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.