PRNP

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PRNP (PRioN Protein (Creutzfeld-Jakob disease, Gerstmann-Sträussler-Scheinker syndrome, fatal familial insomnia)) is a gene that codes for a protein called the prion protein (PrP), which is expressed in the brain and several other tissues.

The human PRNP gene is located on the short (p) arm of chromosome 20 between the end (terminus) of the arm and position 12, from base pair 4,615,068 to base pair 4,630,233.

PRNP has also recently been designated CD230 (cluster of differentiation 230).

For more information about PRNP, read the full article at Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.


News tagged with prion protein


Family's inherited condition links prion diseases, Alzheimer's

Medicine & Health / Neuroscience

created Dec 09, 2009 | popularity 4.5 / 5 (2) | comments 0

(PhysOrg.com) -- A laboratory connection between Alzheimer's disease and brain-wasting diseases such as the human form of mad cow disease has moved into the clinic for what is believed to be the first time, manifesting itself ...





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Targeted therapy prolongs life in patients with HER2-positive breast cancer

Medicine & Health / Cancer

created 12 hours ago | popularity 5 / 5 (1) | comments 0

Lapatinib plus trastuzumab are significantly better than lapatinib alone in extending the lives of breast cancer patients whose tumors are HER2-positive, according to Kimberly Blackwell, M.D., associate professor of medicine ...


Physics rules network dynamics

Physics rules network dynamics

Physics / General Physics

created 13 hours ago | popularity 4.7 / 5 (3) | comments 0

(PhysOrg.com) -- When it comes to the workings of the Web, the brain, or a social network, physics finds universal truths.


Novel drug combo improves breast cancer survival

Medicine & Health / Cancer

created 14 hours ago | popularity not rated yet | comments 0

(AP) -- Some women with very advanced breast cancer may have a new treatment option. A combination of two drugs that more precisely target tumors significantly extended the lives of women who had stopped responding to other ...


Bacterial protein mimics its host to disable a key enzyme (w/ Video)

Biology / Cell & Microbiology

created 15 hours ago | popularity 5 / 5 (2) | comments 0

(PhysOrg.com) -- Bacteria use all sorts of cunning to trick hosts into doing their bidding. One con in their bag of tricks: the molecular mimic. In this ruse, bacteria or their agents look for all purposes like some native ...


Researchers identify a scaffold regulating protein disposal

Chemistry / Biochemistry

created 15 hours ago | popularity not rated yet | comments 0

How does a cell manage to identify and degrade the diverse types of defective proteins and thus protect the body against serious diseases? The researchers Sabine C. Horn, Professor Thomas Sommer, Professor Udo Heinemann and ...


FDA confirms benefits of Crestor in more patients

Medicine & Health / Medications

created 16 hours ago | popularity 4 / 5 (1) | comments 0

(AP) -- Federal scientists say AstraZeneca's cholesterol pill Crestor lowers the risk of heart attack, death and stroke in patients without a history of heart disease, though some safety concerns remain.


Sucking Up To Survive

Sucking Up To Survive

Biology / Plants & Animals

created Dec 10, 2009 | popularity 5 / 5 (5) | comments 0

Shrink a human being down to the size of an insect, and you would no longer be able to sip lemonade from a straw. The forces that hold liquid together would simply be too great to overcome at that tiny scale.


Mechanism discovered by which body's cells encourage tuberculosis infection

Mechanism discovered by which body's cells encourage tuberculosis infection

Medicine & Health / Research

created Dec 10, 2009 | popularity 4 / 5 (1) | comments 0

Scientists have discovered a signaling pathway that tuberculosis bacteria use to coerce disease-fighting cells to switch allegiance and work on their behalf. Epithelial cells line the airways and other surfaces ...


Newly discovered mechanism by which blood clots form

Medicine & Health / Research

created Dec 10, 2009 | popularity not rated yet | comments 0

Polyphosphate from blood platelets plays a key role in inflammation and the formation of blood clots, scientists from the Swedish medical university Karolinska Institutet have shown. The study, which is presented in the prestigious ...


Extended youthfulness as a prevention for Alzheimer's disease

Medicine & Health / Research

created Dec 10, 2009 | popularity 4 / 5 (1) | comments 0

Therapies that can keep us younger longer might also push back the clock on Alzheimer's disease, suggests a new study of mice in the December 11th issue of the journal Cell, a Cell Press publication.



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