News tagged with proteasome
Approved Lymphoma Drug Shows Promise in Early Tests Against Bone Cancer
Nov 05, 2009 |
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(PhysOrg.com) -- A drug already approved for the treatment of lymphoma may also slow the growth of the most deadly bone cancer in children and teens, according to an early-stage study published online today ...
KEAP1 Keeps major cancer-promoting protein at bay
Oct 09, 2009 |
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A tumor-suppressing protein snatches up an important cancer-promoting enzyme and tags it with molecules that condemn it to destruction, a research team led by scientists at The University of Texas M. D. Anderson ...
Researchers identify new, cancer-causing role for protein
Aug 27, 2009 |
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The mainstay immune system protein TRAF6 plays an unexpected, key role activating a cell signaling molecule that in mutant form is associated with cancer growth, researchers at The University of Texas M. D. ...
Researchers Find Tools Needed To Build a Cellular Shredder
May 28, 2009 |
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(PhysOrg.com) -- Yale University researchers have discovered a set of cellular chaperones needed to assemble a proteasome, the cellular workhorse that recycles proteins and is crucial for the existence of all eukaryotic cells.
Search results for proteasome
Finding may explain anti-cancer activity of thiazole antibiotics
Aug 12, 2009 |
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University of Illinois at Chicago College of Medicine researchers have discovered how some recently approved drugs act against cancer cells. The finding may lead to a more effectively targeted anti-cancer strategy.
Diet and lifestyle critical to recovery, says study
Jan 17, 2008 |
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Diet and lifestyle may play a much more significant role in a person’s ability to respond favourably to certain drugs, including some cancer therapies, than previously understood, say scientists.
Inhibitors of Important Tuberculosis Survival Mechanism Identified
Sep 16, 2009 |
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(PhysOrg.com) -- Attempts to eradicate tuberculosis (TB) are stymied by the fact that the disease-causing bacteria have a sophisticated mechanism for surviving dormant in infected cells. Now, a team of scientists ...
Novel drug preventing protein recycling shows potential for treating leukemia
Apr 19, 2007 |
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Researchers from the Children's Cancer Hospital at The University of Texas M. D. Anderson Cancer Center have found that a novel targeted therapy effectively treats acute leukemia in animal models by preventing cancer cells ...
Inhibition of NF-kappa B, a key inflammatory protein, reduced radiation toxicity in zebrafish
Sep 01, 2009 |
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Directly inhibiting the activity of a key protein mediator of inflammation reduced radiation toxicity in zebrafish embryos, and may ultimately be of help to patients receiving radiation therapy, according to researchers from ...
Researchers identify how herpes virus infects host cells
Mar 26, 2008 |
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Virginia Commonwealth University researchers have uncovered new information about how the herpes simplex virus takes control of the host cell, setting the stage for the development of antiviral drugs that serve to fight herpes ...
Researchers discover new antituberculosis compounds
Sep 16, 2009 |
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Attempts to eradicate tuberculosis (TB) are stymied by the fact that the disease-causing bacteria have a sophisticated mechanism for surviving dormant in infected cells. Now, a team of scientists led by researchers from Weill ...
Researchers identify novel mechanism for regulation of gene expression
Biology /
Sep 26, 2008 |
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The Stowers Institute's Conaway Lab has demonstrated that an enzyme called Uch37 is kept in check when it is part of a human chromatin remodeling complex, INO80. The results were published in today's issue of Molecular Ce ...
Self-digestion as a means of survival
Feb 27, 2009 |
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In times of starvation, cells tighten their belts: they start to digest their own proteins and cellular organs. The process - known as autophagy - takes place in special organelles called autophagosomes. It is a strategy ...
Researchers make new finding about how memory is stored
Apr 23, 2008 |
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Researchers at Wake Forest University School of Medicine are the first to show that the location of protein-destroying “machines” in nerve cells in the brain may play an important role in how memories are formed – a finding ...
List of search results for proteasome
